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- γグルタミン酸転移酵素とメタボリックシンドローム,心血管疾患,死亡
Lee DS, Evans JC, Robins SJ, Wilson PW, Albano I, Fox CS, Wang TJ, Benjamin EJ, D'Agostino RB, Vasan RS. Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2007; 27: 127-33 - うつと脳卒中リスク
Salaycik KJ, Kelly-Hayes M, Beiser A, Nguyen AH, Brady SM, Kase CS, Wolf PA. Depressive symptoms and risk of stroke: the Framingham Study. Stroke 2007; 38: 16-21
- 酸化LDLの自己抗体と心血管リスク
Wilson PW, Ben-Yehuda O, McNamara J, Massaro J, Witztum J, Reaven PD. Autoantibodies to oxidized LDL and cardiovascular risk: the Framingham Offspring Study. Atherosclerosis 2006; 189: 364-8 - 足関節上腕血圧比の遺伝力
Murabito JM, Guo CY, Fox CS, D'Agostino RB. Heritability of the ankle-brachial index: the Framingham Offspring study. Am J Epidemiol 2006; 164: 963-8 - 糖尿病とアルツハイマー症発症リスク
Akomolafe A, Beiser A, Meigs JB, Au R, Green RC, Farrer LA, Wolf PA, Seshadri S. Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study. Arch Neurol 2006; 63: 1551-5 - 血中ホスファチジルコリンドコサヘキサエン酸含量と認知症,アルツハイマー疾患のリスク
Schaefer EJ, Bongard V, Beiser AS, Lamon-Fava S, Robins SJ, Au R, Tucker KL, Kyle DJ, Wilson PW, Wolf PA. Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Arch Neurol 2006; 63: 1545-50 - 特性の明確なリポ蛋白関連遺伝子変異体と,頸動脈内膜-中膜厚および狭窄の関係
Elosua R, Cupples LA, Fox CS, Polak JF, D'Agostino RA, Wolf PA, O'Donnell CJ, Ordovas JM. Association between well-characterized lipoprotein-related genetic variants and carotid intimal medial thickness and stenosis: The Framingham Heart Study. Atherosclerosis 2006; 189: 222-8 - 社会関係と炎症マーカー
Loucks EB, Sullivan LM, D'Agostino RB, Larson MG, Berkman LF, Benjamin EJ. Social networks and inflammatory markers in the Framingham Heart Study. J Biosoc Sci 2006; 38: 835-42 - UGT1A1アレル,ビリルビン値と冠動脈疾患の関係
Lin JP, O'Donnell CJ, Schwaiger JP, Cupples LA, Lingenhel A, Hunt SC, Yang S, Kronenberg F. Association between the UGT1A1*28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study. Circulation 2006; 114: 1476-81 - CBS遺伝子31bp VNTRと負荷後ホモシステイン濃度との関係
Lievers KJ, Kluijtmans LA, Blom HJ, Wilson PW, Selhub J, Ordovas JM. Association of a 31 bp VNTR in the CBS gene with postload homocysteine concentrations in the Framingham Offspring Study. Eur J Hum Genet 2006; 14: 1125-9 - 一般住民におけるオステオポンチンの臨床的,心エコー的相関
Arnlöv J, Evans JC, Benjamin EJ, Larson MG, Levy D, Sutherland P, Siwik DA, Wang TJ, Colucci WS, Vasan RS. Clinical and echocardiographic correlates of plasma osteopontin in the community: the Framingham Heart Study. Heart 2006; 92: 1514-5 - インスリン抵抗性,酸化ストレス,高血圧と白血球テロメア長
Demissie S, Levy D, Benjamin EJ, Cupples LA, Gardner JP, Herbert A, Kimura M, Larson MG, Meigs JB, Keaney JF, Aviv A. Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study. Aging Cell 2006; 5: 325-30 - IL-6遺伝子型とインスリン抵抗性の関係をBMIが修飾
Herbert A, Liu C, Karamohamed S, Liu J, Manning A, Fox CS, Meigs JB, Cupples LA. BMI modifies associations of IL-6 genotypes with insulin resistance: the Framingham Study. Obesity (Silver Spring) 2006; 14: 1454-61 - 食習慣の質は成人の体重増加を予測する
Quatromoni PA, Pencina M, Cobain MR, Jacques PF, D'Agostino RB. Dietary quality predicts adult weight gain: findings from the Framingham Offspring Study. Obesity (Silver Spring) 2006; 14: 1383-91 - 末梢および脳アテローム血栓症と異なる血管領域における心血管イベント
Kannel WB, Wolf PA. Peripheral and cerebral atherothrombosis and cardiovascular events in different vascular territories: insights from the Framingham Study. Curr Atheroscler Rep 2006; 8: 317-23 - 1970年代から1990年代の2型糖尿病の発症傾向
Fox CS, Pencina MJ, Meigs JB, Vasan RS, Levitzky YS, D'Agostino RB. Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study. Circulation 2006; 113: 2914-8 - 一般集団での単一遺伝子変異と左室壁厚増加
Morita H, Larson MG, Barr SC, Vasan RS, O'Donnell CJ, Hirschhorn JN, Levy D, Corey D, Seidman CE, Seidman JG, Benjamin EJ. Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study. Circulation 2006; 113: 2697-705 - n6脂肪酸摂取量は,空腹時トリグリセリド値,レムナントリポ蛋白濃度,リポ蛋白粒子サイズへのアポリポプロテインA5の効果を調節する
Lai CQ, Corella D, Demissie S, Cupples LA, Adiconis X, Zhu Y, Parnell LD, Tucker KL, Ordovas JM. Dietary intake of n-6 fatty acids modulates effect of apolipoprotein A5 gene on plasma fasting triglycerides, remnant lipoprotein concentrations, and lipoprotein particle size: the Framingham Heart Study. Circulation 2006; 113: 2062-70 - 心電図上のQRS間隔とうっ血性心不全のリスク
Dhingra R, Pencina MJ, Wang TJ, Nam BH, Benjamin EJ, Levy D, Larson MG, Kannel WB, D'Agostino RB, Vasan RS. Electrocardiographic QRS duration and the risk of congestive heart failure: the Framingham Heart Study. Hypertension 2006; 47: 861-7 - APOA5遺伝子座の変異のアテローム性頸動脈硬化症との関連と,肥満による修飾
Elosua R, Ordovas JM, Cupples LA, Lai CQ, Demissie S, Fox CS, Polak JF, Wolf PA, D'Agostino RB, O'Donnell CJ. Variants at the APOA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study. J Lipid Res 2006; 47: 990-6 - 食品頻度質問表により評価したコリンとベタイン摂取量の血中総ホモシステイン濃度の関係
Cho E, Zeisel SH, Jacques P, Selhub J, Dougherty L, Colditz GA, Willett WC. Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr 2006; 83: 905-11 - 教育レベルと炎症マーカーの関係
Loucks EB, Sullivan LM, Hayes LJ, D'Agostino RB, Larson MG, Vasan RS, Benjamin EJ, Berkman LF. Association of educational level with inflammatory markers in the Framingham Offspring Study. Am J Epidemiol 2006; 163: 622-8 - エストロゲン受容体α変異体は女性のリポ蛋白サイズの分布とリポ蛋白粒子レベルに関係する
Demissie S, Cupples LA, Shearman AM, Gruenthal KM, Peter I, Schmid CH, Karas RH, Housman DE, Mendelsohn ME, Ordovas JM. Estrogen receptor-alpha variants are associated with lipoprotein size distribution and particle levels in women: the Framingham Heart Study. Atherosclerosis 2006; 185: 210-8 - 至適アテローム生成脂質リスクプロフィールの探索
Nam BH, Kannel WB, D'Agostino RB. Search for an optimal atherogenic lipid risk profile: from the Framingham Study. Am J Cardiol 2006; 97: 372-5 - 大脳白質高信号病変体積と認知機能減少の関係
Au R, Massaro JM, Wolf PA, Young ME, Beiser A, Seshadri S, D'Agostino RB, DeCarli C. Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study. Arch Neurol 2006; 63: 246-50 - 内皮機能不全の止血マーカーと2型糖尿病発症リスク
Meigs JB, O'donnell CJ, Tofler GH, Benjamin EJ, Fox CS, Lipinska I, Nathan DM, Sullivan LM, D'Agostino RB, Wilson PW. Hemostatic markers of endothelial dysfunction and risk of incident type 2 diabetes: the Framingham Offspring Study. Diabetes 2006; 55: 530-7 - 弁,弁輪部石灰化と腎機能の横断的関係
Fox CS, Larson MG, Vasan RS, Guo CY, Parise H, Levy D, Leip EP, O'donnell CJ, D'Agostino RB, Benjamin EJ. Cross-sectional association of kidney function with valvular and annular calcification: the Framingham heart study. J Am Soc Nephrol 2006; 17: 521-7 - 脳卒中の生涯リスク
Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Kannel WB, Wolf PA. The lifetime risk of stroke: estimates from the Framingham Study. Stroke 2006; 37: 345-50 - BMIに関連する染色体領域の性・年齢特異的効果
Atwood LD, Heard-Costa NL, Fox CS, Jaquish CE, Cupples LA. Sex and age specific effects of chromosomal regions linked to body mass index in the Framingham Study. BMC Genet 2006; 7: 7 - メタボリックシンドロームと2型糖尿病の脳卒中危険因子としての比較
Najarian RM, Sullivan LM, Kannel WB, Wilson PW, D'Agostino RB, Wolf PA. Metabolic syndrome compared with type 2 diabetes mellitus as a risk factor for stroke: the Framingham Offspring Study. Arch Intern Med 2006; 166: 106-11 - small LDL粒子数の増加:メタボリックシンドロームの著明な特徴
Kathiresan S, Otvos JD, Sullivan LM, Keyes MJ, Schaefer EJ, Wilson PW, D'Agostino RB, Vasan RS, Robins SJ. Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study. Circulation 2006; 113: 20-9 - 腹部大動脈石灰化と手および腰椎の外骨腫症
Karasik D, Kiel DP, Kiely DK, Cupples LA, Wilson PW, O'Donnell CJ, Felson DT. Abdominal aortic calcification and exostoses at the hand and lumbar spine: the Framingham Study. Calcif Tissue Int 2006; 78: 1-8 - 身体活動の糖尿病の有無による寿命との関係
Jonker JT, De Laet C, Franco OH, Peeters A, Mackenbach J, Nusselder WJ. Physical activity and life expectancy with and without diabetes: life table analysis of the Framingham Heart Study. Diabetes Care 2006; 29: 38-43 - 大脳白質高信号領域と全ゲノムスキャン
DeStefano AL, Atwood LD, Massaro JM, Heard-Costa N, Beiser A, Au R, Wolf PA, DeCarli C. Genome-wide scan for white matter hyperintensity: the Framingham Heart Study. Stroke 2006; 37: 77-81
- 末梢微小血管機能,心血管疾患危険因子,冠動脈スティフネスの横断的関係
Mitchell GF, Vita JA, Larson MG, Parise H, Keyes MJ, Warner E, Vasan RS, Levy D, Benjamin EJ. Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study. Circulation 2005; 112: 3722-8 - 自然閉経年齢の全ゲノム連鎖解析
Murabito JM, Yang Q, Fox CS, Cupples LA. Genome-wide linkage analysis to age at natural menopause in a community-based sample: the Framingham Heart Study. Fertil Steril 2005; 84: 1674-9 - HDL調節における遺伝子型・性の相互作用
Mosher MJ, Martin LJ, Cupples LA, Yang Q, Dyer TD, Williams JT, North KE. Genotype-by-sex interaction in the regulation of high-density lipoprotein: the Framingham Heart Study. Hum Biol 2005; 77: 773-93 - エストロゲン関連遺伝子の変異と横断的,縦断的血圧値
Peter I, Shearman AM, Zucker DR, Schmid CH, Demissie S, Cupples LA, Larson MG, Vasan RS, D'Agostino RB, Karas RH, Mendelsohn ME, Housman DE, Levy D. Variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in the Framingham Heart Study. J Hypertens 2005; 23: 2193-200 - 肥満,糖尿病と認知障害
Elias MF, Elias PK, Sullivan LM, Wolf PA, D'Agostino RB. Obesity, diabetes and cognitive deficit: The Framingham Heart Study. Neurobiol Aging 2005; 26 Suppl 1: 11-6 - C反応性蛋白と男女の心血管リスク
Wilson PW, Nam BH, Pencina M, D'Agostino RB, Benjamin EJ, O'Donnell CJ. C-reactive protein and risk of cardiovascular disease in men and women from the Framingham Heart Study. Arch Intern Med 2005; 165: 2473-8 - 凝固系の異常と年齢上昇の関係
Tofler GH, Massaro J, Levy D, Mittleman M, Sutherland P, Lipinska I, Muller JE, D'Agostino RB. Relation of the prothrombotic state to increasing age (from the Framingham Offspring Study). Am J Cardiol 2005; 96: 1280-3 - インスリン抵抗性,メタボリックシンドロームと心血管イベント発症
Rutter MK, Meigs JB, Sullivan LM, D'Agostino RB, Wilson PW. Insulin resistance, the metabolic syndrome, and incident cardiovascular events in the Framingham Offspring Study. Diabetes 2005; 54: 3252-7 - 最高齢者における生存率,無病生存率を予測する心血管危険因子
Terry DF, Pencina MJ, Vasan RS, Murabito JM, Wolf PA, Hayes MK, Levy D, D'Agostino RB, Benjamin EJ. Cardiovascular risk factors predictive for survival and morbidity-free survival in the oldest-old Framingham Heart Study participants. J Am Geriatr Soc 2005; 53: 1944-50 - エストロゲン受容体α遺伝子変異と脂肪過多症の程度の性特異的関係
Fox CS, Yang Q, Cupples LA, Guo CY, Atwood LD, Murabito JM, Levy D, Mendelsohn ME, Housman DE, Shearman AM. Sex-specific association between estrogen receptor-alpha gene variation and measures of adiposity: the Framingham Heart Study. J Clin Endocrinol Metab 2005; 90: 6257-62 - 血清尿酸値に影響する遺伝子の全ゲノム探索
Yang Q, Guo CY, Cupples LA, Levy D, Wilson PW, Fox CS. Genome-wide search for genes affecting serum uric acid levels: the Framingham Heart Study. Metabolism 2005; 54: 1435-41 - 肥満発症の推定リスク
Vasan RS, Pencina MJ, Cobain M, Freiberg MS, D'Agostino RB. Estimated risks for developing obesity in the Framingham Heart Study. Ann Intern Med 2005; 143: 473-80 - 女性および男性におけるアルコール消費量と血小板の活性化および凝集との関係
Mukamal KJ, Massaro JM, Ault KA, Mittleman MA, Sutherland PA, Lipinska I, Levy D, D'Agostino RB, Tofler GH. Alcohol consumption and platelet activation and aggregation among women and men: the Framingham Offspring Study. Alcohol Clin Exp Res 2005; 29: 1906-12 - ホモシステインと認知機能
Elias MF, Sullivan LM, D'Agostino RB, Elias PK, Jacques PF, Selhub J, Seshadri S, Au R, Beiser A, Wolf PA. Homocysteine and cognitive performance in the Framingham offspring study: age is important. Am J Epidemiol 2005; 162: 644-53 - 血管性炎症の全身性バイオマーカーのゲノム探索
Dupuis J, Larson MG, Vasan RS, Massaro JM, Wilson PW, Lipinska I, Corey D, Vita JA, Keaney JF, Benjamin EJ. Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: evidence for susceptibility loci on 1q. Atherosclerosis 2005; 182: 307-14 - RAGE遺伝子のGly82Ser多型は心血管疾患と関係しない
Hofmann MA, Yang Q, Harja E, Kedia P, Gregersen PK, Cupples LA, Schmidt AM, Hudson BI. The RAGE Gly82Ser polymorphism is not associated with cardiovascular disease in the Framingham offspring study. Atherosclerosis 2005; 182: 301-5 - 血糖値と腎疾患の発症
Fox CS, Larson MG, Leip EP, Meigs JB, Wilson PW, Levy D. Glycemic status and development of kidney disease: the Framingham Heart Study. Diabetes Care 2005; 28: 2436-40 - うつ症状,冠動脈疾患と全死亡
Wulsin LR, Evans JC, Vasan RS, Murabito JM, Kelly-Hayes M, Benjamin EJ. Depressive symptoms, coronary heart disease, and overall mortality in the Framingham Heart Study. Psychosom Med 2005; 67: 697-702 - 緊張度,不安感の冠動脈疾患,心房細動,全死亡の10年発症率予測
Eaker ED, Sullivan LM, Kelly-Hayes M, D'Agostino RB, Benjamin EJ. Tension and anxiety and the prediction of the 10-year incidence of coronary heart disease, atrial fibrillation, and total mortality: the Framingham Offspring Study. Psychosom Med 2005; 67: 692-6 - CCL2多型は単球走化性蛋白-1レベルと心筋梗塞に関連する
McDermott DH, Yang Q, Kathiresan S, Cupples LA, Massaro JM, Keaney JF, Larson MG, Vasan RS, Hirschhorn JN, O'Donnell CJ, Murphy PM, Benjamin EJ. CCL2 polymorphisms are associated with serum monocyte chemoattractant protein-1 levels and myocardial infarction in the Framingham Heart Study. Circulation 2005; 112: 1113-20 - 非高血圧,非糖尿病者における軽度アルブミン尿と心血管疾患発症の関係
Arnlöv J, Evans JC, Meigs JB, Wang TJ, Fox CS, Levy D, Benjamin EJ, D'Agostino RB, Vasan RS. Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study. Circulation 2005; 112: 969-75 - -174 IL-6 GG遺伝子型は2型糖尿病のリスク減少と関連する
Herbert A, Liu C, Karamohamed S, Schiller J, Liu J, Yang Q, Wilson PW, Cupples LA, Meigs JB. The -174 IL-6 GG genotype is associated with a reduced risk of type 2 diabetes mellitus in a family sample from the National Heart, Lung and Blood Institute's Framingham Heart Study. Diabetologia 2005; 48: 1492-5 - アルコール脱水素酵素1C多型のアルコール-心血管疾患関係への影響
Djoussé L, Levy D, Herbert AG, Wilson PW, D'Agostino RB, Cupples LA, Karamohamed S, Ellison RC. Influence of alcohol dehydrogenase 1C polymorphism on the alcohol-cardiovascular disease association (from the Framingham Offspring Study). Am J Cardiol 2005; 96: 227-32 - 動脈スティフネス,脈波反射,平均動脈圧の遺伝力と全ゲノム連鎖解析
Mitchell GF, DeStefano AL, Larson MG, Benjamin EJ, Chen MH, Vasan RS, Vita JA, Levy D. Heritability and a genome-wide linkage scan for arterial stiffness, wave reflection, and mean arterial pressure: the Framingham Heart Study. Circulation 2005; 112: 194-9 - 脂質異常のリスク層別化
Kannel WB. Risk stratification of dyslipidemia: insights from the Framingham Study. Curr Med Chem Cardiovasc Hematol Agents 2005; 3: 187-93 - HDL3コレステロールの全ゲノム解析と候補遺伝子の精細マッピング
Yang Q, Lai CQ, Parnell L, Cupples LA, Adiconis X, Zhu Y, Wilson PW, Housman DE, Shearman AM, D'Agostino RB, Ordovas JM. Genome-wide linkage analyses and candidate gene fine mapping for HDL3 cholesterol: the Framingham Study. J Lipid Res 2005; 46: 1416-25 - 過体重成人の体重減少と長期の高血圧リスク
Moore LL, Visioni AJ, Qureshi MM, Bradlee ML, Ellison RC, D'Agostino R. Weight loss in overweight adults and the long-term risk of hypertension: the Framingham study. Arch Intern Med 2005; 165: 1298-303 - 体重変化の全ゲノム連鎖解析
Fox CS, Heard-Costa NL, Vasan RS, Murabito JM, D'Agostino RB, Atwood LD. Genomewide linkage analysis of weight change in the Framingham Heart Study. J Clin Endocrinol Metab 2005; 90: 3197-201 - 自然閉経年齢の遺伝力
Murabito JM, Yang Q, Fox C, Wilson PW, Cupples LA. Heritability of age at natural menopause in the Framingham Heart Study. J Clin Endocrinol Metab 2005; 90: 3427-30 - 血清アルドステロンの臨床的相関と遺伝的相関
Kathiresan S, Larson MG, Benjamin EJ, Corey D, Murabito JM, Fox CS, Wilson PW, Rifai N, Meigs JB, Ricken G, Lifton RP, Levy D, Vasan RS. Clinical and genetic correlates of serum aldosterone in the community: the Framingham Heart Study. Am J Hypertens 2005; 18: 657-65 - アジア-インディアン女性と,白人女性とのHDL-, LDLコレステロールのサブクラスの比較
Bhalodkar NC, Blum S, Rana T, Kitchappa R, Bhalodkar AN, Enas EA. Comparison of high-density and low-density lipoprotein cholesterol subclasses and sizes in Asian Indian women with Caucasian women from the Framingham Offspring Study. Clin Cardiol 2005; 28: 247-51 - 脳形態の計測と梗塞
DeCarli C, Massaro J, Harvey D, Hald J, Tullberg M, Au R, Beiser A, D'Agostino R, Wolf PA. Measures of brain morphology and infarction in the framingham heart study: establishing what is normal. Neurobiol Aging 2005; 26: 491-510 - 拡張期高血圧,収縮期高血圧の新規発症の予測因子
Franklin SS, Pio JR, Wong ND, Larson MG, Leip EP, Vasan RS, Levy D. Predictors of new-onset diastolic and systolic hypertension: the Framingham Heart Study. Circulation 2005; 111: 1121-7 - apo A-IV 360(Gln->His)多型と血清脂質,血清リポ蛋白の関係
Cendoroglo MS, Lahoz C, Martinez TL, Ordovas JM, Lamon-Fava S, Cupples LA, Wilson PW, Schaefer EJ. Association of apo A-IV 360 (Gln --> His) polymorphism with plasma lipids and lipoproteins: the Framingham Offspring Study. Atherosclerosis 2005; 179: 169-75 - 3番染色体の全ゲノム連鎖解析から得られたQT間隔が量的形質遺伝するという証拠
Newton-Cheh C, Larson MG, Corey DC, Benjamin EJ, Herbert AG, Levy D, D'Agostino RB, O'Donnell CJ. QT interval is a heritable quantitative trait with evidence of linkage to chromosome 3 in a genome-wide linkage analysis: The Framingham Heart Study. Heart Rhythm 2005; 2: 277-84 - 心電図上のQRS間隔と左室径の横断的関係
Dhingra R, Ho Nam B, Benjamin EJ, Wang TJ, Larson MG, D'Agostino RB, Levy D, Vasan RS. Cross-sectional relations of electrocardiographic QRS duration to left ventricular dimensions: the Framingham Heart Study. J Am Coll Cardiol 2005; 45: 685-9 - 多価不飽和脂肪酸はPPARA-L162V多型と相互作用し血清トリグリセリドとアポリポプロテインCIII濃度に影響する
Tai ES, Corella D, Demissie S, Cupples LA, Coltell O, Schaefer EJ, Tucker KL, Ordovas JM. Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study. J Nutr 2005; 135: 397-403 - 6q23-24上遺伝子のヘマトクリット値への影響の証拠
Lin JP, O'Donnell CJ, Levy D, Cupples LA. Evidence for a gene influencing haematocrit on chromosome 6q23-24: genomewide scan in the Framingham Heart Study. J Med Genet 2005; 42: 75-9 - 微量アルブミン尿の全ゲノム連鎖解析
Fox CS, Yang Q, Guo CY, Cupples LA, Wilson PW, Levy D, Meigs JB. Genome-wide linkage analysis to urinary microalbuminuria in a community-based sample: the Framingham Heart Study. Kidney Int 2005; 67: 70-4 - 血清コレステロールと認知機能
Elias PK, Elias MF, D'Agostino RB, Sullivan LM, Wolf PA. Serum cholesterol and cognitive performance in the Framingham Heart Study. Psychosom Med 2005; 67: 24-30
- アジア-インディアン男性と,白人男性とのlarge HDL-, small HDLコレステロール値の比較
Bhalodkar NC, Blum S, Rana T, Bhalodkar A, Kitchappa R, Kim KS, Enas E. Comparison of levels of large and small high-density lipoprotein cholesterol in Asian Indian men compared with Caucasian men in the Framingham Offspring Study. Am J Cardiol 2004; 94: 1561-3 - 上腕動脈血管拡張作用と全身性炎症
Vita JA, Keaney JF, Larson MG, Keyes MJ, Massaro JM, Lipinska I, Lehman BT, Fan S, Osypiuk E, Wilson PW, Vasan RS, Mitchell GF, Benjamin EJ. Brachial artery vasodilator function and systemic inflammation in the Framingham Offspring Study. Circulation 2004; 110: 3604-9 - 脳卒中リスクプロフィール,脳重量と認知機能
Seshadri S, Wolf PA, Beiser A, Elias MF, Au R, Kase CS, D'Agostino RB, DeCarli C. Stroke risk profile, brain volume, and cognitive function: the Framingham Offspring Study. Neurology 2004; 63: 1591-9 - 男性におけるHDL亜集団プロフィールと冠動脈疾患有病率
Asztalos BF, Cupples LA, Demissie S, Horvath KV, Cox CE, Batista MC, Schaefer EJ. High-density lipoprotein subpopulation profile and coronary heart disease prevalence in male participants of the Framingham Offspring Study. Arterioscler Thromb Vasc Biol 2004; 24: 2181-7 - APOA5遺伝子座の血清トリグリセリド,リポプロテインサブクラス,心血管疾患リスクへの影響
Lai CQ, Demissie S, Cupples LA, Zhu Y, Adiconis X, Parnell LD, Corella D, Ordovas JM. Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study. J Lipid Res 2004; 45: 2096-105 - 心血管疾患を有しないものでは腎機能は冠動脈石灰化と逆相関する
Fox CS, Larson MG, Keyes MJ, Levy D, Clouse ME, Culleton B, O'Donnell CJ. Kidney function is inversely associated with coronary artery calcification in men and women free of cardiovascular disease: the Framingham Heart Study. Kidney Int 2004; 66: 2017-21 - 心房細動におけるワルファリンとアスピリン使用時の大出血発症予測
Sam C, Massaro JM, D'Agostino RB, Levy D, Lambert JW, Wolf PA, Benjamin EJ. Warfarin and aspirin use and the predictors of major bleeding complications in atrial fibrillation (the Framingham Heart Study). Am J Cardiol 2004; 94: 947-51 - 尿中ナトリウム排泄量と心構造,心肥大との横断的関係
Dhingra R, Pencina MJ, Benjamin EJ, Levy D, Larson MG, Meigs JB, Rifai N, D'Agostino RB, Vasan RS. Cross-sectional relations of urinary sodium excretion to cardiac structure and hypertrophy. The Framingham Heart Study. Am J Hypertens 2004; 17: 891-6 - APOE遺伝子型とアテローム性頸動脈硬化症との関係
Elosua R, Ordovas JM, Cupples LA, Fox CS, Polak JF, Wolf PA, D'Agostino RA, O'Donnell CJ. Association of APOE genotype with carotid atherosclerosis in men and women: the Framingham Heart Study. J Lipid Res 2004; 45: 1868-75 - 血清中総TIMP-1レベルと心血管リスク,心エコー計測値との関係
Sundström J, Evans JC, Benjamin EJ, Levy D, Larson MG, Sawyer DB, Siwik DA, Colucci WS, Wilson PW, Vasan RS. Relations of plasma total TIMP-1 levels to cardiovascular risk factors and echocardiographic measures: the Framingham heart study. Eur Heart J 2004; 25: 1509-16 - 血清クレアチニン値,GFR,クレアチニンクリアランスの全ゲノム連鎖解析
Fox CS, Yang Q, Cupples LA, Guo CY, Larson MG, Leip EP, Wilson PW, Levy D. Genomewide linkage analysis to serum creatinine, GFR, and creatinine clearance in a community-based population: the Framingham Heart Study. J Am Soc Nephrol 2004; 15: 2457-61 - 心房細動の生涯発症リスク
Lloyd-Jones DM, Wang TJ, Leip EP, Larson MG, Levy D, Vasan RS, D'Agostino RB, Massaro JM, Beiser A, Wolf PA, Benjamin EJ. Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation 2004; 110: 1042-6 - 冠動脈疾患死亡と突然死の1950年から1999年までの経時的傾向
Fox CS, Evans JC, Larson MG, Kannel WB, Levy D. Temporal trends in coronary heart disease mortality and sudden cardiac death from 1950 to 1999: the Framingham Heart Study. Circulation 2004; 110: 522-7 - 局所ずり応力と上腕FMD(血流遮断前後の動脈径変化率)
Mitchell GF, Parise H, Vita JA, Larson MG, Warner E, Keaney JF, Keyes MJ, Levy D, Vasan RS, Benjamin EJ. Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study. Hypertension 2004; 44: 134-9 - 脈圧に関する全ゲノム解析
DeStefano AL, Larson MG, Mitchell GF, Benjamin EJ, Vasan RS, Li J, Corey D, Levy D. Genome-wide scan for pulse pressure in the National Heart, Lung and Blood Institute's Framingham Heart Study. Hypertension 2004; 44: 152-5 - 脳卒中リスクプロフィールは白質高信号領域体積を予測する
Jeerakathil T, Wolf PA, Beiser A, Massaro J, Seshadri S, D'Agostino RB, DeCarli C. Stroke risk profile predicts white matter hyperintensity volume: the Framingham Study. Stroke 2004; 35: 1857-61 - 脳内微少出血:その頻度と心血管危険因子との関係
Jeerakathil T, Wolf PA, Beiser A, Hald JK, Au R, Kase CS, Massaro JM, DeCarli C. Cerebral microbleeds: prevalence and associations with cardiovascular risk factors in the Framingham Study. Stroke 2004; 35: 1831-5 - C反応性蛋白,メタボリックシンドロームと心血管イベント予測
Rutter MK, Meigs JB, Sullivan LM, D'Agostino RB, Wilson PW. C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 2004; 110: 380-5 - 細胞間接着分子1の遺伝力と関連性
Keaney JF, Massaro JM, Larson MG, Vasan RS, Wilson PW, Lipinska I, Corey D, Sutherland P, Vita JA, Benjamin EJ. Heritability and correlates of intercellular adhesion molecule-1 in the Framingham Offspring Study. J Am Coll Cardiol 2004; 44: 168-73 - 自律神経系の緊張は心房細動の新規発症と関連するか
Singh JP, Larson MG, Levy D, Evans JC, Tsuji H, Benjamin EJ. Is baseline autonomic tone associated with new onset atrial fibrillation?: Insights from the framingham heart study. Ann Noninvasive Electrocardiol 2004; 9: 215-20 - 核磁気共鳴法で計測したリポプロテインのサブクラスの性・年齢により違い
Freedman DS, Otvos JD, Jeyarajah EJ, Shalaurova I, Cupples LA, Parise H, D'Agostino RB, Wilson PW, Schaefer EJ. Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham Study. Clin Chem 2004; 50: 1189-200 - 白質高信号体積の遺伝的変異
Atwood LD, Wolf PA, Heard-Costa NL, Massaro JM, Beiser A, D'Agostino RB, DeCarli C. Genetic variation in white matter hyperintensity volume in the Framingham Study. Stroke 2004; 35: 1609-13 - 血清マトリクスメタロプロテアーゼ9と臨床的心血管危険因子,左室エコー計測値との関係
Sundström J, Evans JC, Benjamin EJ, Levy D, Larson MG, Sawyer DB, Siwik DA, Colucci WS, Sutherland P, Wilson PW, Vasan RS. Relations of plasma matrix metalloproteinase-9 to clinical cardiovascular risk factors and echocardiographic left ventricular measures: the Framingham Heart Study. Circulation 2004; 109: 2850-6 - 超高齢者における単球サイトカイン産生,全身性炎症と心血管疾患
Haider AW, Roubenoff R, Wilson PW, Levy D, D'Agostino R, Silbershatz H, O'Donnell CJ. Monocyte cytokine production, systemic inflammation and cardiovascular disease in very elderly men and women: the Framingham Heart Study. Eur J Cardiovasc Prev Rehabil 2004; 11: 214-5 - 健常人における加齢による動脈スティフネスと脈波反射の変化
Mitchell GF, Parise H, Benjamin EJ, Larson MG, Keyes MJ, Vita JA, Vasan RS, Levy D. Changes in arterial stiffness and wave reflection with advancing age in healthy men and women: the Framingham Heart Study. Hypertension 2004; 43: 1239-45 - 脳卒中後の認知症
Ivan CS, Seshadri S, Beiser A, Au R, Kase CS, Kelly-Hayes M, Wolf PA. Dementia after stroke: the Framingham Study. Stroke 2004; 35: 1264-8 - 運動誘発性期外収縮の臨床との関連と予後予測能
Morshedi-Meibodi A, Evans JC, Levy D, Larson MG, Vasan RS. Clinical correlates and prognostic significance of exercise-induced ventricular premature beats in the community: the Framingham Heart Study. Circulation 2004; 109: 2417-22 - 職務ストレスは冠動脈疾患や死亡のリスクを上昇させるか
Eaker ED, Sullivan LM, Kelly-Hayes M, D'Agostino RB, Benjamin EJ. Does job strain increase the risk for coronary heart disease or death in men and women? The Framingham Offspring Study. Am J Epidemiol 2004; 159: 950-8 - ウエスト周囲径への6番染色体全ゲノム連鎖解析
Fox CS, Heard-Costa NL, Wilson PW, Levy D, D'Agostino RB, Atwood LD. Genome-wide linkage to chromosome 6 for waist circumference in the Framingham Heart Study. Diabetes 2004; 53: 1399-402 - 心構造への血清アルドステロンの関連:性による違い
Vasan RS, Evans JC, Benjamin EJ, Levy D, Larson MG, Sundstrom J, Murabito JM, Sam F, Colucci WS, Wilson PW. Relations of serum aldosterone to cardiac structure: gender-related differences in the Framingham Heart Study. Hypertension 2004; 43: 957-62 - ヘマトクリット理と左室重量
Amin MG, Tighiouart H, Weiner DE, Stark PC, Griffith JL, MacLeod B, Salem DN, Sarnak MJ. Hematocrit and left ventricular mass: the Framingham Heart study. J Am Coll Cardiol 2004; 43: 1276-82 - 肥満と凝固系異常の関係
Rosito GA, D'Agostino RB, Massaro J, Lipinska I, Mittleman MA, Sutherland P, Wilson PW, Levy D, Muller JE, Tofler GH. Association between obesity and a prothrombotic state: the Framingham Offspring Study. Thromb Haemost 2004; 91: 683-9 - 怒りと敵愾心は男性の心房細動発症を予測する
Eaker ED, Sullivan LM, Kelly-Hayes M, D'Agostino RB, Benjamin EJ. Anger and hostility predict the development of atrial fibrillation in men in the Framingham Offspring Study. Circulation 2004; 109: 1267-71 - 長期アルコール摂取と心房細動リスク
Djoussé L, Levy D, Benjamin EJ, Blease SJ, Russ A, Larson MG, Massaro JM, D'Agostino RB, Wolf PA, Ellison RC. Long-term alcohol consumption and the risk of atrial fibrillation in the Framingham Study. Am J Cardiol 2004; 93: 710-3 - 中手骨皮質領域と冠動脈疾患のリスク
Samelson EJ, Kiel DP, Broe KE, Zhang Y, Cupples LA, Hannan MT, Wilson PW, Levy D, Williams SA, Vaccarino V. Metacarpal cortical area and risk of coronary heart disease: the Framingham Study. Am J Epidemiol 2004; 159: 589-95 - 糖尿病罹病期間の冠動脈疾患死亡への有意な影響
Fox CS, Sullivan L, D'Agostino RB, Wilson PW. The significant effect of diabetes duration on coronary heart disease mortality: the Framingham Heart Study. Diabetes Care 2004; 27: 704-8 - 血清ホモシステインと左室構造,左室機能との関係
Sundström J, Sullivan L, Selhub J, Benjamin EJ, D'Agostino RB, Jacques PF, Rosenberg IH, Levy D, Wilson PW, Vasan RS. Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study. Eur Heart J 2004; 25: 523-30 - 喫煙は心疾患の有無によらず生存期間を減少させる
Mamun AA, Peeters A, Barendregt J, Willekens F, Nusselder W, Bonneux L. Smoking decreases the duration of life lived with and without cardiovascular disease: a life course analysis of the Framingham Heart Study. Eur Heart J 2004; 25: 409-15 - 生物学的加齢への遺伝の寄与
Karasik D, Hannan MT, Cupples LA, Felson DT, Kiel DP. Genetic contribution to biological aging: the Framingham Study. J Gerontol A Biol Sci Med Sci 2004; 59: 218-26 - 凝血因子経路の遺伝子の多型は頸動脈内膜-中膜厚とは関係しない
Fox CS, Larson MG, Corey D, Feng D, Lindpaintner K, Polak JF, Wolf PA, D'Agostino RB, Tofler GH, O'Donnell CJ. Absence of association between polymorphisms in the hemostatic factor pathway genes and carotid intimal medial thickness: the Framingham Heart Study. Stroke 2004; 35: e65-7 - FMD(血流遮断前後の動脈径変化率)の臨床的相関と遺伝力
Benjamin EJ, Larson MG, Keyes MJ, Mitchell GF, Vasan RS, Keaney JF, Lehman BT, Fan S, Osypiuk E, Vita JA. Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study. Circulation 2004; 109: 613-9
- 遺伝的に決定されている肥満発症年齢への連鎖を探索する2つの戦略の比較
Engelman CD, Brady HL, Baron AE, Norris JM. Comparison between two analytic strategies to detect linkage to obesity with genetically determined age of onset: the Framingham Heart Study. BMC Genet 2003; 4 Suppl 1: S90 - 縦断的収縮期血圧表現型とゲノム連鎖解析
James K, Weitzel LR, Engelman CD, Zerbe G, Norris JM. Genome scan linkage results for longitudinal systolic blood pressure phenotypes in subjects from the Framingham Heart Study. BMC Genet 2003; 4 Suppl 1: S83 - 血清ホモシステイン値と高血圧発症,血圧変化
Sundström J, Sullivan L, D'Agostino RB, Jacques PF, Selhub J, Rosenberg IH, Wilson PW, Levy D, Vasan RS. Plasma homocysteine, hypertension incidence, and blood pressure tracking: the Framingham Heart Study. Hypertension 2003; 42: 1100-5 - 肺機能の6q27との連鎖と関係性
Wilk JB, DeStefano AL, Joost O, Myers RH, Cupples LA, Slater K, Atwood LD, Heard-Costa NL, Herbert A, O'Connor GT, Gottlieb DJ. Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart Study. Hum Mol Genet 2003; 12: 2745-51 - 年齢と性はメチレンテトラヒドロ葉酸還元酵素のC677T遺伝子型と空腹時血清ホモシステイン濃度との関係に影響する
Russo GT, Friso S, Jacques PF, Rogers G, Cucinotta D, Wilson PW, Ordovas JM, Rosenberg IH, Selhub J. Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort. J Nutr 2003; 133: 3416-21 - 血中インスリン様成長因子Iと,心筋梗塞歴のない高齢者での心不全リスク
Vasan RS, Sullivan LM, D'Agostino RB, Roubenoff R, Harris T, Sawyer DB, Levy D, Wilson PW. Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study. Ann Intern Med 2003; 139: 642-8 - 超高齢生活者のにおけるサイトカイン,インスリン様成長因子因子I,筋肉減少症と死亡率
Roubenoff R, Parise H, Payette HA, Abad LW, D'Agostino R, Jacques PF, Wilson PW, Dinarello CA, Harris TB. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. Am J Med 2003; 115: 429-35 - 高齢者における足首-上腕血圧指数の脳卒中,冠動脈疾患,死亡リスク
Murabito JM, Evans JC, Larson MG, Nieto K, Levy D, Wilson PW. The ankle-brachial index in the elderly and risk of stroke, coronary disease, and death: the Framingham Study. Arch Intern Med 2003; 163: 1939-42 - インスリン様成長因子Iとインターロイキン6は超高齢生活者の筋肉減少症を予測する
Payette H, Roubenoff R, Jacques PF, Dinarello CA, Wilson PW, Abad LW, Harris T. Insulin-like growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: the Framingham Heart Study. J Am Geriatr Soc 2003; 51: 1237-43 - 新規心房細動発症者における脳卒中もしくは死亡の予測リスクスコア
Wang TJ, Massaro JM, Levy D, Vasan RS, Wolf PA, D'Agostino RB, Larson MG, Kannel WB, Benjamin EJ. A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study. JAMA 2003; 290: 1049-56 - 頸動脈内膜-中膜厚は親の早期冠動脈疾患発症と関連する
Wang TJ, Nam BH, D'Agostino RB, Wolf PA, Lloyd-Jones DM, MacRae CA, Wilson PW, Polak JF, O'Donnell CJ. Carotid intima-media thickness is associated with premature parental coronary heart disease: the Framingham Heart Study. Circulation 2003; 108: 572-6 - 心房細動,うっ血性心不全の経時的関係とその合併が死亡におよぼす影響
Wang TJ, Larson MG, Levy D, Vasan RS, Leip EP, Wolf PA, D'Agostino RB, Murabito JM, Kannel WB, Benjamin EJ. Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study. Circulation 2003; 107: 2920-5 - インスリン分解酵素遺伝子の多型は男性の2型糖尿病と関係する
Karamohamed S, Demissie S, Volcjak J, Liu C, Heard-Costa N, Liu J, Shoemaker CM, Panhuysen CI, Meigs JB, Wilson P, Atwood LD, Cupples LA, Herbert A. Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study. Diabetes 2003; 52: 1562-7 - スカベンジャー受容体クラスBタイプ1遺伝子座の遺伝的変異は血清リポプロテイン濃度と粒子サイズ,2型糖尿病との関係を決定する
Osgood D, Corella D, Demissie S, Cupples LA, Wilson PW, Meigs JB, Schaefer EJ, Coltell O, Ordovas JM. Genetic variation at the scavenger receptor class B type I gene locus determines plasma lipoprotein concentrations and particle size and interacts with type 2 diabetes: the framingham study. J Clin Endocrinol Metab 2003; 88: 2869-79 - アルツハイマー病の危険因子としての血清総コレステロール値
Tan ZS, Seshadri S, Beiser A, Wilson PW, Kiel DP, Tocco M, D'Agostino RB, Wolf PA. Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study. Arch Intern Med 2003; 163: 1053-7 - ドプラー経僧帽弁血流インデックスと心房細動リスク
Vasan RS, Larson MG, Levy D, Galderisi M, Wolf PA, Benjamin EJ. Doppler transmitral flow indexes and risk of atrial fibrillation (the Framingham Heart Study). Am J Cardiol 2003; 91: 1079-83 - 血流中フィブリノーゲン値に影響する遺伝子の全ゲノム探索
Yang Q, Tofler GH, Cupples LA, Larson MG, Feng D, Lindpaintner K, Levy D, D'Agostino RB, O'Donnell CJ. A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study. Thromb Res 2003; 110: 57-64 - 糖尿病と冠動脈疾患危険因子の縦断的解析
Bhargava A. A longitudinal analysis of the risk factors for diabetes and coronary heart disease in the Framingham Offspring Study. Popul Health Metr 2003; 1: 3 - 2番染色体長腕テロメア上の1遺伝子が血清ビリルビンに影響している証拠:全ゲノム探索
Lin JP, Cupples LA, Wilson PW, Heard-Costa N, O'Donnell CJ. Evidence for a gene influencing serum bilirubin on chromosome 2q telomere: a genomewide scan in the Framingham study. Am J Hum Genet 2003; 72: 1029-34 - 糖尿病のない住民におけるインスリンの量的特性に連鎖する遺伝子座のゲノム探索
Panhuysen CI, Cupples LA, Wilson PW, Herbert AG, Myers RH, Meigs JB. A genome scan for loci linked to quantitative insulin traits in persons without diabetes: the Framingham Offspring Study. Diabetologia 2003; 46: 579-87 - 血清BNP値と血圧値の追跡
Freitag MH, Larson MG, Levy D, Benjamin EJ, Wang TJ, Leip EP, Wilson PW, Vasan RS. Plasma brain natriuretic peptide levels and blood pressure tracking in the Framingham Heart Study. Hypertension 2003; 41: 978-83 - 僧帽弁輪石灰化は心血管疾患罹病率,死亡率を予測する
Fox CS, Vasan RS, Parise H, Levy D, O'Donnell CJ, D'Agostino RB, Benjamin EJ. Mitral annular calcification predicts cardiovascular morbidity and mortality: the Framingham Heart Study. Circulation 2003; 107: 1492-6 - 心筋梗塞歴のない高齢者における炎症マーカーと心不全リスク
Vasan RS, Sullivan LM, Roubenoff R, Dinarello CA, Harris T, Benjamin EJ, Sawyer DB, Levy D, Wilson PW, D'Agostino RB. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Circulation 2003; 107: 1486-91 - 血糖値と肺機能の関係
Walter RE, Beiser A, Givelber RJ, O'Connor GT, Gottlieb DJ. Association between glycemic state and lung function: the Framingham Heart Study. Am J Respir Crit Care Med 2003; 167: 911-6 - 肥満と全身性酸化ストレス
Keaney JF, Larson MG, Vasan RS, Wilson PW, Lipinska I, Corey D, Massaro JM, Sutherland P, Vita JA, Benjamin EJ. Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol 2003; 23: 434-9 - 心筋梗塞リスクへの血清アルブミン,ビリルビンの影響
Djoussé L, Rothman KJ, Cupples LA, Levy D, Ellison RC. Effect of serum albumin and bilirubin on the risk of myocardial infarction (the Framingham Offspring Study). Am J Cardiol 2003; 91: 485-8 - 肥満,高血圧存在下での低認知機能
Elias MF, Elias PK, Sullivan LM, Wolf PA, D'Agostino RB. Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study. Int J Obes Relat Metab Disord 2003; 27: 260-8 - アテローム性動脈硬化症表現型への遺伝因子,環境因子の寄与:頸動脈内膜- 中膜厚の遺伝力
Fox CS, Polak JF, Chazaro I, Cupples A, Wolf PA, D'Agostino RA, O'Donnell CJ. Genetic and environmental contributions to atherosclerosis phenotypes in men and women: heritability of carotid intima-media thickness in the Framingham Heart Study. Stroke 2003; 34: 397-401 - 耐糖能異常とインスリン抵抗性の心構造と心機能へのインパクト:性差
Rutter MK, Parise H, Benjamin EJ, Levy D, Larson MG, Meigs JB, Nesto RW, Wilson PW, Vasan RS. Impact of glucose intolerance and insulin resistance on cardiac structure and function: sex-related differences in the Framingham Heart Study. Circulation 2003; 107: 448-54 - うっ血性心不全リスクの予測因子としての収縮期血圧,拡張期血圧,脈圧
Haider AW, Larson MG, Franklin SS, Levy D. Systolic blood pressure, diastolic blood pressure, and pulse pressure as predictors of risk for congestive heart failure in the Framingham Heart Study. Ann Intern Med 2003; 138: 10-6 - 健常成人の身長に影響する遺伝子座の全ゲノム探索
Mukhopadhyay N, Finegold DN, Larson MG, Cupples LA, Myers RH, Weeks DE. A genome-wide scan for loci affecting normal adult height in the Framingham Heart Study. Hum Hered 2003; 55: 191-201
- 心拍変動に連鎖するゲノムの探索
Singh JP, Larson MG, O'Donnell CJ, Tsuji H, Corey D, Levy D. Genome scan linkage results for heart rate variability (the Framingham Heart Study). Am J Cardiol 2002; 90: 1290-3 - うっ血性心不全の生涯発症リスク
Lloyd-Jones DM, Larson MG, Leip EP, Beiser A, D'Agostino RB, Kannel WB, Murabito JM, Vasan RS, Benjamin EJ, Levy D. Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation 2002; 106: 3068-72 - 心筋梗塞と全死亡リスクと血清アルブミン
Djoussé L, Rothman KJ, Cupples LA, Levy D, Ellison RC. Serum albumin and risk of myocardial infarction and all-cause mortality in the Framingham Offspring Study. Circulation 2002; 106: 2919-24 - 高齢者での高鉄貯蔵リスクに関連する食品因子
Fleming DJ, Tucker KL, Jacques PF, Dallal GE, Wilson PW, Wood RJ. Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort. Am J Clin Nutr 2002; 76: 1375-84 - 28年間のBMIに対する全ゲノム連鎖解析
Atwood LD, Heard-Costa NL, Cupples LA, Jaquish CE, Wilson PW, D'Agostino RB. Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study. Am J Hum Genet 2002; 71: 1044-50 - 食品からの脂肪摂取は肝性リパーゼ遺伝子プロモータの多型のHDL代謝に対する効果を決定する
Ordovas JM, Corella D, Demissie S, Cupples LA, Couture P, Coltell O, Wilson PW, Schaefer EJ, Tucker KL. Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: evidence of a strong dose effect in this gene-nutrient interaction in the Framingham Study. Circulation 2002; 106: 2315-21 - トレッドミル運動テスト後の心拍数の回復と心血管疾患イベントのリスク
Morshedi-Meibodi A, Larson MG, Levy D, O'Donnell CJ, Vasan RS. Heart rate recovery after treadmill exercise testing and risk of cardiovascular disease events (The Framingham Heart Study). Am J Cardiol 2002; 90: 848-52 - 一般住民における僧帽弁逸脱:心エコーで認められる良性の状態
Freed LA, Benjamin EJ, Levy D, Larson MG, Evans JC, Fuller DL, Lehman B, Levine RA. Mitral valve prolapse in the general population: the benign nature of echocardiographic features in the Framingham Heart Study. J Am Coll Cardiol 2002; 40: 1298-304 - 腹部大動脈石灰沈着はうっ血性心不全のリスク上昇に関連する
Walsh CR, Cupples LA, Levy D, Kiel DP, Hannan M, Wilson PW, O'Donnell CJ. Abdominal aortic calcific deposits are associated with increased risk for congestive heart failure: the Framingham Heart Study. Am Heart J 2002; 144: 733-9 - C反応性蛋白とアテローム性頸動脈硬化症の関係
Wang TJ, Nam BH, Wilson PW, Wolf PA, Levy D, Polak JF, D'Agostino RB, O'Donnell CJ. Association of C-reactive protein with carotid atherosclerosis in men and women: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2002; 22: 1662-7 - 空腹時,糖負荷時血糖と心血管疾患リスク
Meigs JB, Nathan DM, D'Agostino RB, Wilson PW. Fasting and postchallenge glycemia and cardiovascular disease risk: the Framingham Offspring Study. Diabetes Care 2002; 25: 1845-50 - 血清ナトリウム利尿ペプチドによる左室肥大と収縮不全のスクリーニング
Vasan RS, Benjamin EJ, Larson MG, Leip EP, Wang TJ, Wilson PW, Levy D. Plasma natriuretic peptides for community screening for left ventricular hypertrophy and systolic dysfunction: the Framingham heart study. JAMA 2002; 288: 1252-9 - C反応性蛋白は無症候性心外膜冠動脈石灰化と関連する
Wang TJ, Larson MG, Levy D, Benjamin EJ, Kupka MJ, Manning WJ, Clouse ME, D'Agostino RB, Wilson PW, O'Donnell CJ. C-reactive protein is associated with subclinical epicardial coronary calcification in men and women: the Framingham Heart Study. Circulation 2002; 106: 1189-91 - 全粒粉摂取は2型糖尿病と心血管疾患の代謝危険因子によい影響を与える
McKeown NM, Meigs JB, Liu S, Wilson PW, Jacques PF. Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study. Am J Clin Nutr 2002; 76: 390-8 - 2型糖尿病とインスリン抵抗性における冠動脈石灰化
Meigs JB, Larson MG, D'Agostino RB, Levy D, Clouse ME, Nathan DM, Wilson PW, O'Donnell CJ. Coronary artery calcification in type 2 diabetes and insulin resistance: the framingham offspring study. Diabetes Care 2002; 25: 1313-9 - 腹部大動脈石灰沈着の遺伝力の証拠
O'Donnell CJ, Chazaro I, Wilson PW, Fox C, Hannan MT, Kiel DP, Cupples LA. Evidence for heritability of abdominal aortic calcific deposits in the Framingham Heart Study. Circulation 2002; 106: 337-41 - 末梢動脈障害の有病率と臨床関連因子
Murabito JM, Evans JC, Nieto K, Larson MG, Levy D, Wilson PW. Prevalence and clinical correlates of peripheral arterial disease in the Framingham Offspring Study. Am Heart J 2002; 143: 961-5 - 僧帽弁逸脱と心房中隔動脈瘤
Freed LA, Levy D, Levine RA, Evans JC, Larson MG, Fuller DL, Lehman B, Benjamin EJ. Mitral valve prolapse and atrial septal aneurysm: an evaluation in the Framingham Heart Study. Am J Cardiol 2002; 89: 1326-9 - 糖尿病患者においてはレムナント様リポ蛋白コレステロール値とトリグリセリド値が上昇している
Schaefer EJ, McNamara JR, Shah PK, Nakajima K, Cupples LA, Ordovas JM, Wilson PW. Elevated remnant-like particle cholesterol and triglyceride levels in diabetic men and women in the Framingham Offspring Study. Diabetes Care 2002; 25: 989-94 - 血糖症と微量アルブミン尿の長期的関係
Meigs JB, D'Agostino RB, Nathan DM, Rifai N, Wilson PW. Longitudinal association of glycemia and microalbuminuria: the Framingham Offspring Study. Diabetes Care 2002; 25: 977-83 - 血清カリウム値と心血管疾患リスク
Walsh CR, Larson MG, Leip EP, Vasan RS, Levy D. Serum potassium and risk of cardiovascular disease: the Framingham heart study. Arch Intern Med 2002; 162: 1007-12 - アテローム性大動脈硬化症の年齢と性の分布:磁気共鳴イメージング検査
Jaffer FA, O'Donnell CJ, Larson MG, Chan SK, Kissinger KV, Kupka MJ, Salton C, Botnar RM, Levy D, Manning WJ. Age and sex distribution of subclinical aortic atherosclerosis: a magnetic resonance imaging examination of the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2002; 22: 849-54 - PPARA L162V多型と血清脂質値の関係
Tai ES, Demissie S, Cupples LA, Corella D, Wilson PW, Schaefer EJ, Ordovas JM. Association between the PPARA L162V polymorphism and plasma lipid levels: the Framingham Offspring Study. Arterioscler Thromb Vasc Biol 2002; 22: 805-10 - アルコール消費量と虚血性脳卒中のリスク
Djoussé L, Ellison RC, Beiser A, Scaramucci A, D'Agostino RB, Wolf PA. Alcohol consumption and risk of ischemic stroke: The Framingham Study. Stroke 2002; 33: 907-12 - 非高血圧成人集団における正常な左室構造と性差;心血管磁気共鳴調査
Salton CJ, Chuang ML, O'Donnell CJ, Kupka MJ, Larson MG, Kissinger KV, Edelman RR, Levy D, Manning WJ. Gender differences and normal left ventricular anatomy in an adult population free of hypertension. A cardiovascular magnetic resonance study of the Framingham Heart Study Offspring cohort. J Am Coll Cardiol 2002; 39: 1055-60 - 肺機能に影響する遺伝子座:全ゲノム探索
Joost O, Wilk JB, Cupples LA, Harmon M, Shearman AM, Baldwin CT, O'Connor GT, Myers RH, Gottlieb DJ. Genetic loci influencing lung function: a genome-wide scan in the Framingham Study. Am J Respir Crit Care Med 2002; 165: 795-9 - 白人住民における血清グルコース値とHbA1cに関連する遺伝子座の全ゲノム探索
Meigs JB, Panhuysen CI, Myers RH, Wilson PW, Cupples LA. A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study. Diabetes 2002; 51: 833-40 - 心血管の生活史:オリジナルコホートの生活経過解析
Peeters A, Mamun AA, Willekens F, Bonneux L. A cardiovascular life history. A life course analysis of the original Framingham Heart Study cohort. Eur Heart J 2002; 23: 458-66 - 中年の余寿命における高血圧発症リスク
Vasan RS, Beiser A, Seshadri S, Larson MG, Kannel WB, D'Agostino RB, Levy D. Residual lifetime risk for developing hypertension in middle-aged women and men: The Framingham Heart Study. JAMA 2002; 287: 1003-10 - アルコール摂取量とうっ血性心不全のリスク
Walsh CR, Larson MG, Evans JC, Djousse L, Ellison RC, Vasan RS, Levy D. Alcohol consumption and risk for congestive heart failure in the Framingham Heart Study. Ann Intern Med 2002; 136: 181-91 - 血清カリウム値は長期間追跡血圧値と関係しない
Walsh CR, Larson MG, Vasan RS, Levy D. Serum potassium is not associated with blood pressure tracking in the Framingham Heart Study. Am J Hypertens 2002; 15: 130-6 - 植物性エストロゲンの食品からの摂取は閉経後女性の代謝性心血管リスクプロフィールによい影響を与える
de Kleijn MJ, van der Schouw YT, Wilson PW, Grobbee DE, Jacques PF. Dietary intake of phytoestrogens is associated with a favorable metabolic cardiovascular risk profile in postmenopausal U.S.women: the Framingham study. J Nutr 2002; 132: 276-82 - 多価不飽和脂肪酸はAPOA1 G-A多型のHDLコレステロール濃度におよぼす影響を性特異的に修飾する
Ordovas JM, Corella D, Cupples LA, Demissie S, Kelleher A, Coltell O, Wilson PW, Schaefer EJ, Tucker K. Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham Study. Am J Clin Nutr 2002; 75: 38-46 - 以前の血圧値と心血管疾患のリスク
Vasan RS, Massaro JM, Wilson PW, Seshadri S, Wolf PA, Levy D, D'Agostino RB. Antecedent blood pressure and risk of cardiovascular disease: the Framingham Heart Study . Circulation 2002; 105: 48-53
- 腸型脂肪酸結合蛋白のA/T54多型と血清脂質の変化の関係
Galluzzi JR, Cupples LA, Otvos JD, Wilson PW, Schaefer EJ, Ordovas JM. Association of the A/T54 polymorphism in the intestinal fatty acid binding protein with variations in plasma lipids in the Framingham Offspring Study. Atherosclerosis 2001; 159: 417-24 - 葉酸添加物は赤血球葉酸濃度を上昇させる
Choumenkovitch SF, Jacques PF, Nadeau MR, Wilson PW, Rosenberg IH, Selhub J. Folic acid fortification increases red blood cell folate concentrations in the Framingham study. J Nutr 2001; 131: 3277-80 - 非高血圧者における高血圧発症頻度の評価
Vasan RS, Larson MG, Leip EP, Kannel WB, Levy D. Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study. Lancet 2001; 358: 1682-6 - 肺機能の経時的変化の遺伝力
Gottlieb DJ, Wilk JB, Harmon M, Evans JC, Joost O, Levy D, O'Connor GT, Myers RH. Heritability of longitudinal change in lung function. The Framingham study. Am J Respir Crit Care Med 2001; 164: 1655-9 - 血清C反応性蛋白濃度と虚血性脳卒中,一過性脳虚血発作のリスク
Rost NS, Wolf PA, Kase CS, Kelly-Hayes M, Silbershatz H, Massaro JM, D'Agostino RB, Franzblau C, Wilson PW. Plasma concentration of C-reactive protein and risk of ischemic stroke and transient ischemic attack: the Framingham study. Stroke 2001; 32: 2575-9 - 中年期の血圧上昇は老年における脳卒中のリスクを上昇させる
Seshadri S, Wolf PA, Beiser A, Vasan RS, Wilson PW, Kase CS, Kelly-Hayes M, Kannel WB, D'Agostino RB. Elevated midlife blood pressure increases stroke risk in elderly persons: the Framingham Study. Arch Intern Med 2001; 161: 2343-50 - 睡眠呼吸障害における右心の心エコー特性
Guidry UC, Mendes LA, Evans JC, Levy D, O'Connor GT, Larson MG, Gottlieb DJ, Benjamin EJ. Echocardiographic features of the right heart in sleep-disordered breathing: the Framingham Heart Study. Am J Respir Crit Care Med 2001; 164: 933-8 - APOC3遺伝子座上のSst-I多型の,脂質値の変動,リポプロテインサブクラスのプロフィールと冠動脈疾患リスクとの関係
Russo GT, Meigs JB, Cupples LA, Demissie S, Otvos JD, Wilson PW, Lahoz C, Cucinotta D, Couture P, Mallory T, Schaefer EJ, Ordovas JM. Association of the Sst-I polymorphism at the APOC3 gene locus with variations in lipid levels, lipoprotein subclass profiles and coronary heart disease risk: the Framingham offspring study. Atherosclerosis 2001; 158: 173-81 - インスリン抵抗症候群における空腹時血清ホモシステイン値
Meigs JB, Jacques PF, Selhub J, Singer DE, Nathan DM, Rifai N, D'Agostino RB, Wilson PW. Fasting plasma homocysteine levels in the insulin resistance syndrome: the Framingham offspring study. Diabetes Care 2001; 24: 1403-10 - 血小板糖蛋白IIIa Pl(a)多型,フィブリノーゲンと血小板凝集性
Feng D, Lindpaintner K, Larson MG, O'Donnell CJ, Lipinska I, Sutherland PA, Mittleman M, Muller JE, D'Agostino RB, Levy D, Tofler GH. Platelet glycoprotein IIIa Pl(a) polymorphism, fibrinogen, and platelet aggregability: The Framingham Heart Study. Circulation 2001; 104: 140-4 - 腸型脂肪酸結合蛋白のAla54-Thr多型と糖負荷2時間後インスリン値の関係
Galluzzi JR, Cupples LA, Meigs JB, Wilson PW, Schaefer EJ, Ordovas JM. Association of the Ala54-Thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study. Diabetes Care 2001; 24: 1161-6 - 血小板凝集への遺伝,環境の寄与
O'Donnell CJ, Larson MG, Feng D, Sutherland PA, Lindpaintner K, Myers RH, D'Agostino RA, Levy D, Tofler GH. Genetic and environmental contributions to platelet aggregation: the Framingham heart study. Circulation 2001; 103: 3051-6 - 米国の閉経後女性では食品からの植物性エストロゲン摂取量が低い
de Kleijn MJ, van der Schouw YT, Wilson PW, Adlercreutz H, Mazur W, Grobbee DE, Jacques PF. Intake of dietary phytoestrogens is low in postmenopausal women in the United States: the Framingham study(1-4). J Nutr 2001; 131: 1826-32 - 血清総ビリルビンと心血管疾患リスク
Djoussé L, Levy D, Cupples LA, Evans JC, D'Agostino RB, Ellison RC. Total serum bilirubin and risk of cardiovascular disease in the Framingham offspring study. Am J Cardiol 2001; 87: 1196-200; A4, 7 - コレステロール低下一次予防試験の一般住民への適用性
Lloyd-Jones DM, O'Donnell CJ, D'Agostino RB, Massaro J, Silbershatz H, Wilson PW. Applicability of cholesterol-lowering primary prevention trials to a general population: the framingham heart study. Arch Intern Med 2001; 161: 949-54 - アルコール摂取は男性のAPOE遺伝子座のLDLコレステロール濃度への影響を決定する
Corella D, Tucker K, Lahoz C, Coltell O, Cupples LA, Wilson PW, Schaefer EJ, Ordovas JM. Alcohol drinking determines the effect of the APOE locus on LDL-cholesterol concentrations in men: the Framingham Offspring Study. Am J Clin Nutr 2001; 73: 736-45 - 血圧の冠動脈疾患リスクとの相関は加齢によって変化するか
Franklin SS, Larson MG, Khan SA, Wong ND, Leip EP, Kannel WB, Levy D. Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart Study. Circulation 2001; 103: 1245-9 - 自由生活高齢者の鉄分状態:貯蔵鉄増加の高有病率に伴う鉄過剰群
Fleming DJ, Jacques PF, Tucker KL, Massaro JM, D'Agostino RB, Wilson PW, Wood RJ. Iron status of the free-living, elderly Framingham Heart Study cohort: an iron-replete population with a high prevalence of elevated iron stores. Am J Clin Nutr 2001; 73: 638-46 - アポリポ蛋白E遺伝子型と心血管疾患
Lahoz C, Schaefer EJ, Cupples LA, Wilson PW, Levy D, Osgood D, Parpos S, Pedro-Botet J, Daly JA, Ordovas JM. Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study. Atherosclerosis 2001; 154: 529-37 - 止血因子の状態と心房細動
Feng D, D'Agostino RB, Silbershatz H, Lipinska I, Massaro J, Levy D, Benjamin EJ, Wolf PA, Tofler GH. Hemostatic state and atrial fibrillation (the Framingham Offspring Study). Am J Cardiol 2001; 87: 168-71 - レムナント様リポ蛋白コレステロールは女性の独立した心血管疾患リスクである
McNamara JR, Shah PK, Nakajima K, Cupples LA, Wilson PW, Ordovas JM, Schaefer EJ. Remnant-like particle (RLP) cholesterol is an independent cardiovascular disease risk factor in women: results from the Framingham Heart Study. Atherosclerosis 2001; 154: 229-36
- アルコール摂取量と間欠性跛行のリスク
Djoussé L, Levy D, Murabito JM, Cupples LA, Ellison RC. Alcohol consumption and risk of intermittent claudication in the Framingham Heart Study. Circulation 2000; 102: 3092-7 - 2型糖尿病の親からの伝達
Meigs JB, Cupples LA, Wilson PW. Parental transmission of type 2 diabetes: the Framingham Offspring Study. Diabetes 2000; 49: 2201-7 - 17番染色体の血圧に影響する遺伝子の証拠:縦断的血圧表現型のゲノム連鎖探索の結果から
Levy D, DeStefano AL, Larson MG, O'Donnell CJ, Lifton RP, Gavras H, Cupples LA, Myers RH. Evidence for a gene influencing blood pressure on chromosome 17. Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the framingham heart study. Hypertension 2000; 36: 477-83 - 高血糖症と心拍変動の減少の関係
Singh JP, Larson MG, O'Donnell CJ, Wilson PF, Tsuji H, Lloyd-Jones DM, Levy D. Association of hyperglycemia with reduced heart rate variability (The Framingham Heart Study). Am J Cardiol 2000; 86: 309-12 - 7番染色体q32.3-qter上の遺伝子がTG/HDL-C比に影響をおよぼす証拠:全ゲノム探索
Shearman AM, Ordovas JM, Cupples LA, Schaefer EJ, Harmon MD, Shao Y, Keen JD, DeStefano AL, Joost O, Wilson PW, Housman DE, Myers RH. Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham study. Hum Mol Genet 2000; 9: 1315-20 - 失神の危険因子
Chen L, Chen MH, Larson MG, Evans J, Benjamin EJ, Levy D. Risk factors for syncope in a community-based sample (the Framingham Heart Study). Am J Cardiol 2000; 85: 1189-93 - コレステリルエステル転送蛋白-TaqIB多型のリポプロテインサブクラスの変動と冠動脈疾患リスクとの関係
Ordovas JM, Cupples LA, Corella D, Otvos JD, Osgood D, Martinez A, Lahoz C, Coltell O, Wilson PW, Schaefer EJ. Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: the Framingham study. Arterioscler Thromb Vasc Biol 2000; 20: 1323-9 - アポリポ蛋白Eアイソフォーム多型はインスリン抵抗性とは関係しない
Meigs JB, Ordovas JM, Cupples LA, Singer DE, Nathan DM, Schaefer EJ, Wilson PW. Apolipoprotein E isoform polymorphisms are not associated with insulin resistance: the Framingham Offspring Study. Diabetes Care 2000; 23: 669-74 - 肝性リパーゼ遺伝子C-514T多型のリポ蛋白サブクラスプロフィールとの関係
Couture P, Otvos JD, Cupples LA, Lahoz C, Wilson PW, Schaefer EJ, Ordovas JM. Association of the C-514T polymorphism in the hepatic lipase gene with variations in lipoprotein subclass profiles: The Framingham Offspring Study. Arterioscler Thromb Vasc Biol 2000; 20: 815-22 - 血清ビタミンB12濃度は食品からの摂取と関連する
Tucker KL, Rich S, Rosenberg I, Jacques P, Dallal G, Wilson PW, Selhub J. Plasma vitamin B-12 concentrations relate to intake source in the Framingham Offspring study. Am J Clin Nutr 2000; 71: 514-22 - 第VII因子遺伝子多型,第VII因子レベルと心血管疾患有病率
Feng D, Tofler GH, Larson MG, O'Donnell CJ, Lipinska I, Schmitz C, Sutherland PA, Johnstone MT, Muller JE, D'Agostino RB, Levy D, Lindpaintner K. Factor VII gene polymorphism, factor VII levels, and prevalent cardiovascular disease: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2000; 20: 593-600 - ミクロゾームトリグリセリド遺伝子プロモーターの遺伝的変異と血清リポ蛋白には関連はない
Couture P, Otvos JD, Cupples LA, Wilson PW, Schaefer EJ, Ordovas JM. Absence of association between genetic variation in the promoter of the microsomal triglyceride transfer protein gene and plasma lipoproteins in the Framingham Offspring Study. Atherosclerosis 2000; 148: 337-43 - 高インスリン血症,高血糖と凝固系の障害
Meigs JB, Mittleman MA, Nathan DM, Tofler GH, Singer DE, Murphy-Sheehy PM, Lipinska I, D'Agostino RB, Wilson PW. Hyperinsulinemia, hyperglycemia, and impaired hemostasis: the Framingham Offspring Study. JAMA 2000; 283: 221-8 - 高血圧のリスク層別化
Kannel WB. Risk stratification in hypertension: new insights from the Framingham Study. Am J Hypertens 2000; 13: 3S-10S - 血清ホモシステインとビタミン状態の関連
Selhub J, Jacques PF, Bostom AG, Wilson PW, Rosenberg IH. Relationship between plasma homocysteine and vitamin status in the Framingham study population. Impact of folic acid fortification. Public Health Rev 2000; 28: 117-45
- Q波心筋梗塞後のイベント発生率の経時的傾向
Guidry UC, Evans JC, Larson MG, Wilson PW, Murabito JM, Levy D. Temporal trends in event rates after Q-wave myocardial infarction: the Framingham Heart Study. Circulation 1999; 100: 2054-9 - 55歳から70歳の住民では障害が減少し健康状態が改善している証拠
Allaire SH, LaValley MP, Evans SR, O'Connor GT, Kelly-Hayes M, Meenan RF, Levy D, Felson DT. Evidence for decline in disability and improved health among persons aged 55 to 70 years: the Framingham Heart Study. Am J Public Health 1999; 89: 1678-83 - JNC VIの血圧とリスク群の交差分類のFHSでの検討
Lloyd-Jones DM, Evans JC, Larson MG, O'Donnell CJ, Wilson PW, Levy D. Cross-classification of JNC VI blood pressure stages and risk groups in the Framingham Heart Study. Arch Intern Med 1999; 159: 2206-12 - コレステロール7α水酸化酵素遺伝子のA-204C多型と血清LDLコレステロール値の変化の関係
Couture P, Otvos JD, Cupples LA, Wilson PW, Schaefer EJ, Ordovas JM. Association of the A-204C polymorphism in the cholesterol 7alpha-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study. J Lipid Res 1999; 40: 1883-9 - アルコール摂取量と認知機能
Elias PK, Elias MF, D'Agostino RB, Silbershatz H, Wolf PA. Alcohol consumption and cognitive performance in the Framingham Heart Study. Am J Epidemiol 1999; 150: 580-9 - 高齢者における非空腹時血清総ホモシステイン値と脳卒中発症率
Bostom AG, Rosenberg IH, Silbershatz H, Jacques PF, Selhub J, D'Agostino RB, Wilson PW, Wolf PA. Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: the Framingham Study. Ann Intern Med 1999; 131: 352-5 - 血清クレアチニン値上昇の有病率と関連因子
Culleton BF, Larson MG, Evans JC, Wilson PW, Barrett BJ, Parfrey PS, Levy D. Prevalence and correlates of elevated serum creatinine levels: the Framingham Heart Study. Arch Intern Med 1999; 159: 1785-90 - 脈圧は冠動脈疾患リスク予測に有用か
Franklin SS, Khan SA, Wong ND, Larson MG, Levy D. Is pulse pressure useful in predicting risk for coronary heart Disease? The Framingham heart study. Circulation 1999; 100: 354-60 - 血清尿酸値と心血管疾患,死亡リスク
Culleton BF, Larson MG, Kannel WB, Levy D. Serum uric acid and risk for cardiovascular disease and death: the Framingham Heart Study. Ann Intern Med 1999; 131: 7-13 - リポ蛋白(a)-コレステロールと冠動脈疾患
Seman LJ, DeLuca C, Jenner JL, Cupples LA, McNamara JR, Wilson PW, Castelli WP, Ordovas JM, Schaefer EJ. Lipoprotein(a)-cholesterol and coronary heart disease in the Framingham Heart Study. Clin Chem 1999; 45: 1039-46 - リポ蛋白リパーゼの一般的なトランケーション変異体(Ser447X)は冠動脈疾患に保護的に働く¶
Gagné SE, Larson MG, Pimstone SN, Schaefer EJ, Kastelein JJ, Wilson PW, Ordovas JM, Hayden MR. A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: the Framingham Offspring Study. Clin Genet 1999; 55: 450-4 - 心拍変動の遺伝力
Singh JP, Larson MG, O'Donnell CJ, Tsuji H, Evans JC, Levy D. Heritability of heart rate variability: the Framingham Heart Study. Circulation 1999; 99: 2251-4 - 左室拡大および左室肥大と変時不全の関係
Lauer MS, Larson MG, Evans JC, Levy D. Association of left ventricular dilatation and hypertrophy with chronotropic incompetence in the Framingham Heart Study. Am Heart J 1999; 137: 903-9 - 新規高血圧発症リスクとしてのトレッドミル試験中の血圧反応
Singh JP, Larson MG, Manolio TA, O'Donnell CJ, Lauer M, Evans JC, Levy D. Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. The Framingham heart study. Circulation 1999; 99: 1831-6 - 血小板凝集性増加の血小板GPIIIa PlA2多型との関連
Feng D, Lindpaintner K, Larson MG, Rao VS, O'Donnell CJ, Lipinska I, Schmitz C, Sutherland PA, Silbershatz H, D'Agostino RB, Muller JE, Myers RH, Levy D, Tofler GH. Increased platelet aggregability associated with platelet GPIIIa PlA2 polymorphism: the Framingham Offspring Study. Arterioscler Thromb Vasc Biol 1999; 19: 1142-7 - 僧帽弁,三尖弁,大動脈逆流の有病率と決定要因
Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL, Lehman B, Benjamin EJ. Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study) Am J Cardiol 1999; 83: 897-902 - 慢性咳の心筋梗塞リスクとの関係
Haider AW, Larson MG, O'Donnell CJ, Evans JC, Wilson PW, Levy D. The association of chronic cough with the risk of myocardial infarction: the Framingham Heart Study. Am J Med 1999; 106: 279-84
- 耐糖能異常,末梢動脈疾患の身体的特徴と心血管イベントリスク
Brand FN, Kannel WB, Evans J, Larson MG, Wolf PA. Glucose intolerance, physical signs of peripheral artery disease, and risk of cardiovascular events: the Framingham Study. Am Heart J 1998; 136: 919-27 - 高血圧者におけるCa拮抗薬と死亡リスク
Abascal VM, Larson MG, Evans JC, Blohm AT, Poli K, Levy D. Calcium antagonists and mortality risk in men and women with hypertension in the Framingham Heart Study. Arch Intern Med 1998; 158: 1882-6 - 死亡リスクへの心房細動の影響
Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation 1998; 98: 946-52 - 因果効果のG-estimation:収縮期高血圧と心血管死亡
Witteman JC, D'Agostino RB, Stijnen T, Kannel WB, Cobb JC, de Ridder MA, Hofman A, Robins JM. G-estimation of causal effects: isolated systolic hypertension and cardiovascular death in the Framingham Heart Study. Am J Epidemiol 1998; 148: 390-401 - 心拍変動の減少と新規高血圧発症:高血圧の病因
Singh JP, Larson MG, Tsuji H, Evans JC, O'Donnell CJ, Levy D. Reduced heart rate variability and new-onset hypertension: insights into pathogenesis of hypertension: the Framingham Heart Study. Hypertension 1998; 32: 293-7 - 片頭痛への視覚症状の随伴は高齢者ではまれではない
Wijman CA, Wolf PA, Kase CS, Kelly-Hayes M, Beiser AS. Migrainous visual accompaniments are not rare in late life: the Framingham Study. Stroke 1998; 29: 1539-43 - 体重と死亡率の関係への喫煙の影響
Sempos CT, Durazo-Arvizu R, McGee DL, Cooper RS, Prewitt TE. The influence of cigarette smoking on the association between body weight and mortality. The Framingham Heart Study revisited. Ann Epidemiol 1998; 8: 289-300 - レムナントリポ蛋白コレステロールとトリグリセリドの基準値
McNamara JR, Shah PK, Nakajima K, Cupples LA, Wilson PW, Ordovas JM, Schaefer EJ. Remnant lipoprotein cholesterol and triglyceride reference ranges from the Framingham Heart Study. Clin Chem 1998; 44: 1224-32 - アンジオテンシン変換酵素遺伝子座は男性では高血圧と血圧値に対する関連性と連鎖はあるが女性ではないという証拠
O'Donnell CJ, Lindpaintner K, Larson MG, Rao VS, Ordovas JM, Schaefer EJ, Myers RH, Levy D. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study. Circulation 1998; 97: 1766-72 - 家族間における肺機能の分離比分析
Givelber RJ, Couropmitree NN, Gottlieb DJ, Evans JC, Levy D, Myers RH, O'Connor GT. Segregation analysis of pulmonary function among families in the Framingham Study. Am J Respir Crit Care Med 1998; 157: 1445-51 - 超高齢者における体脂肪量と骨格筋量の身体障害との関係
Visser M, Harris TB, Langlois J, Hannan MT, Roubenoff R, Felson DT, Wilson PW, Kiel DP. Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci 1998; 53: M214-21 - 自由生活高齢者における鉄貯蔵の食事の決定因子
Fleming DJ, Jacques PF, Dallal GE, Tucker KL, Wilson PW, Wood RJ. Dietary determinants of iron stores in a free-living elderly population: The Framingham Heart Study. Am J Clin Nutr 1998; 67: 722-33 - 非糖尿病の耐糖能異常領域では代謝危険因子が連続的に悪化する
Meigs JB, Nathan DM, Wilson PW, Cupples LA, Singer DE. Metabolic risk factors worsen continuously across the spectrum of nondiabetic glucose tolerance. The Framingham Offspring Study. Ann Intern Med 1998; 128: 524-33 - 脳卒中後の知性の低下
Kase CS, Wolf PA, Kelly-Hayes M, Kannel WB, Beiser A, D'Agostino RB. Intellectual decline after stroke: the Framingham Study. Stroke 1998; 29: 805-12 - 初発脳卒中後20年以上の生存率と機能の状態
Gresham GE, Kelly-Hayes M, Wolf PA, Beiser AS, Kase CS, D'Agostino RB. Survival and functional status 20 or more years after first stroke: the Framingham Study. Stroke 1998; 29: 793-7
- 認知症とアルツハイマーの生涯リスク
Seshadri S, Wolf PA, Beiser A, Au R, McNulty K, White R, D'Agostino RB. Lifetime risk of dementia and Alzheimer's disease. The impact of mortality on risk estimates in the Framingham Study. Neurology 1997; 49: 1498-504 - 左室重量の遺伝力
Post WS, Larson MG, Myers RH, Galderisi M, Levy D. Heritability of left ventricular mass: the Framingham Heart Study. Hypertension 1997; 30: 1025-8 - 一般住民におけるレイノー現象の頻度
Brand FN, Larson MG, Kannel WB, McGuirk JM. The occurrence of Raynaud's phenomenon in a general population: the Framingham Study. Vasc Med 1997; 2: 296-301 - インスリン抵抗性へのリスク変量の集積
Meigs JB, D'Agostino RB, Wilson PW, Cupples LA, Nathan DM, Singer DE. Risk variable clustering in the insulin resistance syndrome. The Framingham Offspring Study. Diabetes 1997; 46: 1594-600 - 心エコー計測値の参照値をもとにした分布とカテゴリー化
Vasan RS, Larson MG, Levy D, Evans JC, Benjamin EJ. Distribution and categorization of echocardiographic measurements in relation to reference limits: the Framingham Heart Study: formulation of a height- and sex-specific classification and its prospective validation. Circulation 1997; 96: 1863-73 - 低認知機能のリスクとしてのNIDDMと血圧
Elias PK, Elias MF, D'Agostino RB, Cupples LA, Wilson PW, Silbershatz H, Wolf PA. NIDDM and blood pressure as risk factors for poor cognitive performance. The Framingham Study. Diabetes Care 1997; 20: 1388-95 - 変時不全と予後への喫煙の関係
Lauer MS, Pashkow FJ, Larson MG, Levy D. Association of cigarette smoking with chronotropic incompetence and prognosis in the Framingham Heart Study. Circulation 1997; 96: 897-903 - 血圧の年齢変化に伴う血行動態パターン
Franklin SS, Gustin W, Wong ND, Larson MG, Weber MA, Kannel WB, Levy D. Hemodynamic patterns of age-related changes in blood pressure. The Framingham Heart Study. Circulation 1997; 96: 308-15 - 間欠性跛行のリスクプロフィール
Murabito JM, D'Agostino RB, Silbershatz H, Wilson WF. Intermittent claudication. A risk profile from The Framingham Heart Study. Circulation 1997; 96: 44-9 - 認知機能に対する年齢,教育,性の役割
Elias MF, Elias PK, D'Agostino RB, Silbershatz H, Wolf PA. Role of age, education, and gender on cognitive performance in the Framingham Heart Study: community-based norms. Exp Aging Res 1997; 23: 201-35 - インスリン様成長因子Iの身体組成,体重歴,過去の健康行動
Harris TB, Kiel D, Roubenoff R, Langlois J, Hannan M, Havlik R, Wilson P. Association of insulin-like growth factor-I with body composition, weight history, and past health behaviors in the very old: the Framingham Heart Study. J Am Geriatr Soc 1997; 45: 133-9
- BMIの冠動脈疾患への影響
Lamon-Fava S, Wilson PW, Schaefer EJ. Impact of body mass index on coronary heart disease risk factors in men and women. The Framingham Offspring Study. Arterioscler Thromb Vasc Biol 1996; 16: 1509-15 - 心イベントリスクへの心拍変動減少の影響
Tsuji H, Larson MG, Venditti FJ, Manders ES, Evans JC, Feldman CL, Levy D. Impact of reduced heart rate variability on risk for cardiac events. The Framingham Heart Study. Circulation 1996; 94: 2850-5 - 食事摂取と血清葉酸,ホモシステイン濃度との関係
Tucker KL, Selhub J, Wilson PW, Rosenberg IH. Dietary intake pattern relates to plasma folate and homocysteine concentrations in the Framingham Heart Study. J Nutr 1996; 126: 3025-31 - 糖尿病におけるリポ蛋白,アポリポ蛋白,低密度リポ蛋白のサイズ
Siegel RD, Cupples A, Schaefer EJ, Wilson PW. Lipoproteins, apolipoproteins, and low-density lipoprotein size among diabetics in the Framingham offspring study. Metabolism 1996; 45: 1267-72 - 心房細動例における脳卒中の重症度
Lin HJ, Wolf PA, Kelly-Hayes M, Beiser AS, Kase CS, Benjamin EJ, D'Agostino RB. Stroke severity in atrial fibrillation. The Framingham Study. Stroke 1996; 27: 1760-4 - 市販されている免疫比濁法アッセイによる血清リポ蛋白(a)の分布
Contois JH, Lammi-Keefe CJ, Vogel S, McNamara JR, Wilson PW, Massov T, Schaefer EJ. Plasma lipoprotein(a) distribution in the Framingham Offspring Study as determined with a commercially available immunoturbidimetric assay. Clin Chim Acta 1996; 253: 21-35 - 心筋梗塞前後における狭心症の疫学的評価
Brand FN, Larson M, Friedman LM, Kannel WB, Castelli WP. Epidemiologic assessment of angina before and after myocardial infarction: The Framingham study. Am Heart J 1996; 132: 174-8 - 負荷漸増法による運動での心拍反応の障害:変時不全の予後
Lauer MS, Okin PM, Larson MG, Evans JC, Levy D. Impaired heart rate response to graded exercise. Prognostic implications of chronotropic incompetence in the Framingham Heart Study. Circulation 1996; 93: 1520-6 - 心房細動有病率の長期的傾向
Wolf PA, Benjamin EJ, Belanger AJ, Kannel WB, Levy D, D'Agostino RB. Secular trends in the prevalence of atrial fibrillation: The Framingham Study. Am Heart J 1996; 131: 790-5 - オリジナルコホートにおける糖化ヘモグロビンの追跡
Meigs JB, Nathan DM, Cupples LA, Wilson PW, Singer DE. Tracking of glycated hemoglobin in the original cohort of the Framingham Heart Study. J Clin Epidemiol 1996; 49: 411-7 - 血清ホモシステイン,ビタミンの状態と頭蓋外頸動脈狭窄との関係
Selhub J, Jacques PF, Bostom AG, D'Agostino RB, Wilson PW, Belanger AJ, O'Leary DH, Wolf PA, Rush D, Schaefer EJ, Rosenberg IH. Relationship between plasma homocysteine, vitamin status and extracranial carotid-artery stenosis in the Framingham Study population. J Nutr 1996; 126: 1258S-65S - 中年男女が75歳まで生存する因子
Goldberg RJ, Larson M, Levy D. Factors associated with survival to 75 years of age in middle-aged men and women. The Framingham Study. Arch Intern Med 1996; 156: 505-9 - アポリポ蛋白Eイプシロン4の認知症との関連
Myers RH, Schaefer EJ, Wilson PW, D'Agostino R, Ordovas JM, Espino A, Au R, White RF, Knoefel JE, Cobb JL, McNulty KA, Beiser A, Wolf PA. Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study. Neurology 1996; 46: 673-7 - 心血管疾患発症と死亡の性・時間的傾向:1950年-1989年
Sytkowski PA, D'Agostino RB, Belanger A, Kannel WB. Sex and time trends in cardiovascular disease incidence and mortality: the Framingham Heart Study, 1950-1989. Am J Epidemiol 1996; 143: 338-50 - 長期間持続高血圧,長期治療と心血管死亡の長期的傾向:1950−1990
Sytkowski PA, D'Agostino RB, Belanger AJ, Kannel WB. Secular trends in long-term sustained hypertension, long-term treatment, and cardiovascular mortality. The Framingham Heart Study 1950 to 1990. Circulation 1996; 93: 697-703
- 大動脈起始部サイズの心エコー基準値
Vasan RS, Larson MG, Benjamin EJ, Levy D. Echocardiographic reference values for aortic root size: the Framingham Heart Study. J Am Soc Echocardiogr 1995; 8: 793-800 - 男性におけるはげと冠動脈疾患の率
Herrera CR, D'Agostino RB, Gerstman BB, Bosco LA, Belanger AJ. Baldness and coronary heart disease rates in men from the Framingham Study. Am J Epidemiol 1995; 142: 828-33 - 神経心理検査,認知機能,血圧と年齢
Elias MF, D'Agostino RB, Elias PK, Wolf PA. Neuropsychological test performance, cognitive functioning, blood pressure, and age: the Framingham Heart Study. Exp Aging Res 1995; 21: 369-91 - 原因不明のQ波漸進的発症パターン
Murabito JM, Larson MG, Lin ST, Evans JC, Levy D. Unexplained gradual-onset Q wave patterns. A case series from the Framingham Study. J Electrocardiol 1995; 28: 267-75 - 認知症とアルツハイマー症発症への教育の効果
Cobb JL, Wolf PA, Au R, White R, D'Agostino RB. The effect of education on the incidence of dementia and Alzheimer's disease in the Framingham Study. Neurology 1995; 45: 1707-12 - 新規心房細動の診断と急性脳卒中
Lin HJ, Wolf PA, Benjamin EJ, Belanger AJ, D'Agostino RB. Newly diagnosed atrial fibrillation and acute stroke. The Framingham Study. Stroke 1995; 26: 1527-30 - 左房サイズと脳卒中,死亡のリスク
Benjamin EJ, D'Agostino RB, Belanger AJ, Wolf PA, Levy D. Left atrial size and the risk of stroke and death. The Framingham Heart Study. Circulation 1995; 92: 835-41 - 脳卒中発症の時間的パターン
Kelly-Hayes M, Wolf PA, Kase CS, Brand FN, McGuirk JM, D'Agostino RB. Temporal patterns of stroke onset. The Framingham Study. Stroke 1995; 26: 1343-7 - 左房サイズへの血圧の影響
Vaziri SM, Larson MG, Lauer MS, Benjamin EJ, Levy D. Influence of blood pressure on left atrial size. The Framingham Heart Study. Hypertension 1995; 25: 1155-60 - コレステロールと死亡とのU字型関係への喫煙の役割
D'Agostino RB, Belanger AJ, Kannel WB, Higgins M. Role of smoking in the U-shaped relation of cholesterol to mortality in men. The Framingham Study. Am J Epidemiol 1995; 141: 822-7 - エストロゲン状態の上昇と線溶系亢進関係
Gebara OC, Mittleman MA, Sutherland P, Lipinska I, Matheney T, Xu P, Welty FK, Wilson PW, Levy D, Muller JE, et al.. Association between increased estrogen status and increased fibrinolytic potential in the Framingham Offspring Study. Circulation 1995; 91: 1952-8 - 左室の形態と予後
Krumholz HM, Larson M, Levy D. Prognosis of left ventricular geometric patterns in the Framingham Heart Study. J Am Coll Cardiol 1995; 25: 879-84 - 心エコー上の大動脈起始部サイズ決定因子
Vasan RS, Larson MG, Levy D. Determinants of echocardiographic aortic root size. The Framingham Heart Study. Circulation 1995; 91: 734-40 - 食事と心血管疾患危険因子の長期傾向
Posner BM, Franz MM, Quatromoni PA, Gagnon DR, Sytkowski PA, D'Agostino RB, Cupples LA. Secular trends in diet and risk factors for cardiovascular disease: the Framingham Study. J Am Diet Assoc 1995; 95: 171-9
- アポリポ蛋白Eアレル,脂質異常と冠動脈疾患
Wilson PW, Myers RH, Larson MG, Ordovas JM, Wolf PA, Schaefer EJ. Apolipoprotein E alleles, dyslipidemia, and coronary heart disease. The Framingham Offspring Study. JAMA 1994; 272: 1666-71 - 運動は高齢者の死亡率を抑制するか
Sherman SE, D'Agostino RB, Cobb JL, Kannel WB. Does exercise reduce mortality rates in the elderly? Experience from the Framingham Heart Study. Am Heart J 1994; 128: 965-72 - 女性における身体活動と死亡率
Sherman SE, D'Agostino RB, Cobb JL, Kannel WB. Physical activity and mortality in women in the Framingham Heart Study. Am Heart J 1994; 128: 879-84 - 低身長と死亡,心血管疾患イベントリスク
Kannam JP, Levy D, Larson M, Wilson PW. Short stature and risk for mortality and cardiovascular disease events. The Framingham Heart Study. Circulation 1994; 90: 2241-7 - 高血圧発症を予測する血行動態因子
Post WS, Larson MG, Levy D. Hemodynamic predictors of incident hypertension. The Framingham Heart Study. Hypertension 1994; 24: 585-90 - 総コレステロールとHDLコレステロールの年齢変化の決定因子
Wilson PW, Anderson KM, Harris T, Kannel WB, Castelli WP. Determinants of change in total cholesterol and HDL-C with age: the Framingham Study. J Gerontol 1994; 49: M252-7 - 身体活動と脳卒中リスク
Kiely DK, Wolf PA, Cupples LA, Beiser AS, Kannel WB. Physical activity and stroke risk: the Framingham Study. Am J Epidemiol 1994; 140: 608-20 - 女性における電気泳動検索によるリポ蛋白(a)上昇と心血管疾患の前向き研究
Bostom AG, Gagnon DR, Cupples LA, Wilson PW, Jenner JL, Ordovas JM, Schaefer EJ, Castelli WP. A prospective investigation of elevated lipoprotein (a) detected by electrophoresis and cardiovascular disease in women. The Framingham Heart Study. Circulation 1994; 90: 1688-95 - 血清カリウム,マグネシウムと心室期外収縮の関係
Tsuji H, Venditti FJ, Evans JC, Larson MG, Levy D. The associations of levels of serum potassium and magnesium with ventricular premature complexes (the Framingham Heart Study). Am J Cardiol 1994; 74: 232-5 - 高齢者コホートにおける心拍変動減少と死亡リスク
Tsuji H, Venditti FJ, Manders ES, Evans JC, Larson MG, Feldman CL, Levy D. Reduced heart rate variability and mortality risk in an elderly cohort. The Framingham Heart Study. Circulation 1994; 90: 878-83 - 高齢者コホートにおける左室重量と脳卒中リスク
Bikkina M, Levy D, Evans JC, Larson MG, Benjamin EJ, Wolf PA, Castelli WP. Left ventricular mass and risk of stroke in an elderly cohort. The Framingham Heart Study. JAMA 1994; 272: 33-6 - アポリポ蛋白E表現型と血清リポ蛋白値の関係への性と閉経状態の効果
Schaefer EJ, Lamon-Fava S, Johnson S, Ordovas JM, Schaefer MM, Castelli WP, Wilson PW. Effects of gender and menopausal status on the association of apolipoprotein E phenotype with plasma lipoprotein levels. Results from the Framingham Offspring Study. Arterioscler Thromb 1994; 14: 1105-13 - 高血圧発症への左室形態の影響
Post WS, Larson MG, Levy D. Impact of left ventricular structure on the incidence of hypertension. The Framingham Heart Study. Circulation 1994; 90: 179-85 - 長期コレステロール個人内変動:自然経過と有病率,死亡率への悪影響
Kreger BE, Odell PM, D'Agostino RB, Wilson PF. Long-term intraindividual cholesterol variability: natural course and adverse impact on morbidity and mortality--the Framingham Study. Am Heart J 1994; 127: 1607-14 - 頭蓋外アテローム性頸動脈硬化症の危険因子
Fine-Edelstein JS, Wolf PA, O'Leary DH, Poehlman H, Belanger AJ, Kase CS, D'Agostino RB. Precursors of extracranial carotid atherosclerosis in the Framingham Study. Neurology 1994; 44: 1046-50 - HDLコレステロールとアポリポ蛋白A-I値の低値,高値に関連する因子
Schaefer EJ, Lamon-Fava S, Ordovas JM, Cohn SD, Schaefer MM, Castelli WP, Wilson PW. Factors associated with low and elevated plasma high density lipoprotein cholesterol and apolipoprotein A-I levels in the Framingham Offspring Study. J Lipid Res 1994; 35: 871-82 - 年齢,性,閉経状態の血清LDLコレステロールとアポリポ蛋白B値に与える影響
Schaefer EJ, Lamon-Fava S, Cohn SD, Schaefer MM, Ordovas JM, Castelli WP, Wilson PW. Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study. J Lipid Res 1994; 35: 779-92 - 心房細動の独立危険因子
Benjamin EJ, Levy D, Vaziri SM, D'Agostino RB, Belanger AJ, Wolf PA. Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study. JAMA 1994; 271: 840-4 - ヘマトクリットと心血管疾患リスク
Gagnon DR, Zhang TJ, Brand FN, Kannel WB. Hematocrit and the risk of cardiovascular disease--the Framingham study: a 34-year follow-up. Am Heart J 1994; 127: 674-82 - 特定の病状による高齢者の機能的制約の影響
Guccione AA, Felson DT, Anderson JJ, Anthony JM, Zhang Y, Wilson PW, Kelly-Hayes M, Wolf PA, Kreger BE, Kannel WB. The effects of specific medical conditions on the functional limitations of elders in the Framingham Study. Am J Public Health 1994; 84: 351-8 - 非リウマチ性心房細動の心エコー図予測因子
Vaziri SM, Larson MG, Benjamin EJ, Levy D. Echocardiographic predictors of nonrheumatic atrial fibrillation. The Framingham Heart Study. Circulation 1994; 89: 724-30 - 脳卒中リスクプロフィール:降圧治療の補正
D'Agostino RB, Wolf PA, Belanger AJ, Kannel WB. Stroke risk profile: adjustment for antihypertensive medication. The Framingham Study. Stroke 1994; 25: 40-3
- 高血圧の心理学的予測因子:緊張は高血圧に関係するか
Markovitz JH, Matthews KA, Kannel WB, Cobb JL, D'Agostino RB. Psychological predictors of hypertension in the Framingham Study. Is there tension in hypertension? JAMA 1993; 270: 2439-43 - 左室拡張期充満のドップラーインデックスにおよぼす心拍数とPR間隔の影響
Galderisi M, Benjamin EJ, Evans JC, D'Agostino RB, Fuller DL, Lehman B, Levy D. Impact of heart rate and PR interval on Doppler indexes of left ventricular diastolic filling in an elderly cohort (the Framingham Heart Study). Am J Cardiol 1993; 72: 1183-7 - 脂質プロフィールへの女性ホルモン使用の影響
Vaziri SM, Evans JC, Larson MG, Wilson PW. The impact of female hormone usage on the lipid profile. The Framingham Offspring Study. Arch Intern Med 1993; 153: 2200-6 - 体重減少の利点と悪影響
Higgins M, D'Agostino R, Kannel W, Cobb J, Pinsky J. Benefits and adverse effects of weight loss. Observations from the Framingham Study. Ann Intern Med 1993; 119: 758-63 - 心不全の疫学
Ho KK, Pinsky JL, Kannel WB, Levy D. The epidemiology of heart failure: the Framingham Study. J Am Coll Cardiol 1993; 22: 6A-13A - 境界域収縮期高血圧の高齢者における左室形態と拡張期充満の心エコー図評価
Sagie A, Benjamin EJ, Galderisi M, Larson MG, Evans JC, Fuller DL, Lehman B, Levy D. Echocardiographic assessment of left ventricular structure and diastolic filling in elderly subjects with borderline isolated systolic hypertension (the Framingham Heart Study). Am J Cardiol 1993; 72: 662-5 - 血圧値の未治療は認知機能と逆相関する
Elias MF, Wolf PA, D'Agostino RB, Cobb J, White LR. Untreated blood pressure level is inversely related to cognitive functioning: the Framingham Study. Am J Epidemiol 1993; 138: 353-64 - 脳卒中の長期的傾向
Wolf PA, D'Agostino RB. Secular trends in stroke in the Framingham Study. Ann Epidemiol 1993; 3: 471-5 - 脳卒中の家族集積性
Kiely DK, Wolf PA, Cupples LA, Beiser AS, Myers RH. Familial aggregation of stroke. The Framingham Study. Stroke 1993; 24: 1366-71 - 女性における健康な脂肪過多症
Garrison RJ. Healthy adiposity in women: the Framingham Offspring Study. J Am Coll Nutr 1993; 12: 357-62 - 喫煙の健康リスク
Freund KM, Belanger AJ, D'Agostino RB, Kannel WB. The health risks of smoking. The Framingham Study: 34 years of follow-up. Ann Epidemiol 1993; 3: 417-24 - うっ血性心不全発症後の生存率
Ho KK, Anderson KM, Kannel WB, Grossman W, Levy D. Survival after the onset of congestive heart failure in Framingham Heart Study subjects. Circulation 1993; 88: 107-15 - 高齢者の心血管疾患リスクとメディケアコストとの関係
Schauffler HH, D'Agostino RB, Kannel WB. Risk for cardiovascular disease in the elderly and associated Medicare costs: the Framingham Study. Am J Prev Med 1993; 9: 146-54 - 正常血圧者の長期血圧傾向
Kannel WB, Garrison RJ, Dannenberg AL. Secular blood pressure trends in normotensive persons: the Framingham Study. Am Heart J 1993; 125: 1154-8 - 高血圧者における心拍数の死亡率への影響
Gillman MW, Kannel WB, Belanger A, D'Agostino RB. Influence of heart rate on mortality among persons with hypertension: the Framingham Study. Am Heart J 1993; 125: 1148-54 - 血清リポ蛋白(a)値への年齢,性,閉経状態の影響
Jenner JL, Ordovas JM, Lamon-Fava S, Schaefer MM, Wilson PW, Castelli WP, Schaefer EJ. Effects of age, sex, and menopausal status on plasma lipoprotein(a) levels. The Framingham Offspring Study. Circulation 1993; 87: 1135-41 - 先行する心血管状態と初発心筋梗塞後の長期予後
Cupples LA, Gagnon DR, Wong ND, Ostfeld AM, Kannel WB. Preexisting cardiovascular conditions and long-term prognosis after initial myocardial infarction: the Framingham Study. Am Heart J 1993; 125: 863-72 - 高齢者における高コレステロール血症と冠動脈リスク
Wilson PW, Kannel WB. Hypercholesterolemia and Coronary Risk in the Elderly: The Framingham Study. Am J Geriatr Cardiol 1993; 2: 56 - 一般住民における認知症と推定アルツハイマー症の発症
Bachman DL, Wolf PA, Linn RT, Knoefel JE, Cobb JL, Belanger AJ, White LR, D'Agostino RB. Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study. Neurology 1993; 43: 515-9 - 女性における食事,閉経,血清コレステロール値
Posner BM, Cupples LA, Miller DR, Cobb JL, Lutz KJ, D'Agostino RB. Diet, menopause, and serum cholesterol levels in women: the Framingham Study. Am Heart J 1993; 125: 483-9 - 学歴と冠動脈疾患
Garrison RJ, Gold RS, Wilson PW, Kannel WB. Educational attainment and coronary heart disease risk: the Framingham Offspring Study. Prev Med 1993; 22: 54-64
- 無症候性心室不整脈の予後
Bikkina M, Larson MG, Levy D. Prognostic implications of asymptomatic ventricular arrhythmias: the Framingham Heart Study. Ann Intern Med 1992; 117: 990-6 - LDL粒子サイズのばらつき
Campos H, Blijlevens E, McNamara JR, Ordovas JM, Posner BM, Wilson PW, Castelli WP, Schaefer EJ. LDL particle size distribution. Results from the Framingham Offspring Study. Arterioscler Thromb 1992; 12: 1410-9 - 左室拡張機能のドプラー指標の観察者内,観察者間の再現性
Galderisi M, Benjamin EJ, Evans JC, D'Agostino RB, Fuller DL, Lehman B, Wolf PA, Levy D. Intra- and interobserver reproducibility of Doppler-assessed indexes of left ventricular diastolic function in a population-based study (the Framingham Heart Study). Am J Cardiol 1992; 70: 1341-6 - 明らかな心血管疾患のない男性における無症候性左室拡張と収縮不全の予後
Lauer MS, Evans JC, Levy D. Prognostic implications of subclinical left ventricular dilatation and systolic dysfunction in men free of overt cardiovascular disease (the Framingham Heart Study). Am J Cardiol 1992; 70: 1180-4 - 脳卒中イベントと死亡の長期傾向
Wolf PA, D'Agostino RB, O'Neal MA, Sytkowski P, Kase CS, Belanger AJ, Kannel WB. Secular trends in stroke incidence and mortality. The Framingham Study. Stroke 1992; 23: 1551-5 - 冠動脈疾患患者の臨床転帰の心エコー図決定因子
Galderisi M, Lauer MS, Levy D. Echocardiographic determinants of clinical outcome in subjects with coronary artery disease (the Framingham Heart Study). Am J Cardiol 1992; 70: 971-6 - 初発心筋梗塞後の予後:Q波,非Q波心筋梗塞の比較
Berger CJ, Murabito JM, Evans JC, Anderson KM, Levy D. Prognosis after first myocardial infarction. Comparison of Q-wave and non-Q-wave myocardial infarction in the Framingham Heart Study. JAMA 1992; 268: 1545-51 - QT間隔の心拍数による補正の改善手法
Sagie A, Larson MG, Goldberg RJ, Bengtson JR, Levy D. An improved method for adjusting the QT interval for heart rate (the Framingham Heart Study) Am J Cardiol 1992; 70: 797-801 - 健常人における左室拡張機能のドプラー指標決定因子
Benjamin EJ, Levy D, Anderson KM, Wolf PA, Plehn JF, Evans JC, Comai K, Fuller DL, Sutton MS. Determinants of Doppler indexes of left ventricular diastolic function in normal subjects (the Framingham Heart Study). Am J Cardiol 1992; 70: 508-15 - 高齢者における機能制限と障害
Kelly-Hayes M, Jette AM, Wolf PA, D'Agostino RB, Odell PM. Functional limitations and disability among elders in the Framingham Study. Am J Public Health 1992; 82: 841-5 - 禁煙の予測因子
Freund KM, D'Agostino RB, Belanger AJ, Kannel WB, Stokes J. Predictors of smoking cessation: the Framingham Study. Am J Epidemiol 1992; 135: 957-64 - 女性における心筋梗塞と冠動脈疾患死亡:20年間追跡による女性の心理社会的予測因子
Eaker ED, Pinsky J, Castelli WP. Myocardial infarction and coronary death among women: psychosocial predictors from a 20-year follow-up of women in the Framingham Study. Am J Epidemiol 1992; 135: 854-64 - 心血管疾患と白血球数
Kannel WB, Anderson K, Wilson PW. White blood cell count and cardiovascular disease. Insights from the Framingham Study. JAMA 1992; 267: 1253-6 - 運動負荷時血圧反応と左室重量の間には関連性はあるか
Lauer MS, Levy D, Anderson KM, Plehn JF. Is there a relationship between exercise systolic blood pressure response and left ventricular mass? The Framingham Heart Study. Ann Intern Med 1992; 116: 203-10 - 心血管疾患の有病率とHbA1cの関係
Singer DE, Nathan DM, Anderson KM, Wilson PW, Evans JC. Association of HbA1c with prevalent cardiovascular disease in the original cohort of the Framingham Heart Study. Diabetes 1992; 41: 202-8 - 脂質と冠動脈疾患のリスク
Castelli WP, Anderson K, Wilson PW, Levy D. Lipids and risk of coronary heart disease. The Framingham Study. Ann Epidemiol 1992; 2: 23-8 - 高齢者におけるコレステロールとアテローム性頸動脈硬化症
O'Leary DH, Anderson KM, Wolf PA, Evans JC, Poehlman HW. Cholesterol and carotid atherosclerosis in older persons: the Framingham Study. Ann Epidemiol 1992; 2: 147-53 - 左室肥大と死亡率
Kannel WB, Cobb J. Left ventricular hypertrophy and mortality--results from the Framingham Study. Cardiology 1992; 81: 291-8 - 心エコー上の左室肥大:臨床的特徴
Levy D, Murabito JM, Anderson KM, Christiansen JC, Castelli WP. Echocardiographic left ventricular hypertrophy: clinical characteristics. The Framingham Heart Study. Clin Exp Hypertens A 1992; 14: 85-97 - 肥満と軽症高血圧の独立および合併した左室重量と左室形態におよぼす影響
Lauer MS, Anderson KM, Levy D. Separate and joint influences of obesity and mild hypertension on left ventricular mass and geometry: the Framingham Heart Study. J Am Coll Cardiol 1992; 19: 130-4 - 認知症および推定アルツハイマー型老年性認知症の有病率
Bachman DL, Wolf PA, Linn R, Knoefel JE, Cobb J, Belanger A, D'Agostino RB, White LR. Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham Study. Neurology 1992; 42: 115-9
- 心筋梗塞後の予後予測因子としての血清コレステロール
Wong ND, Wilson PW, Kannel WB. Serum cholesterol as a prognostic factor after myocardial infarction: the Framingham Study. Ann Intern Med 1991; 115: 687-93 - 同時測定および30年間血圧値の左室重量と左室形態におよぼす影響
Lauer MS, Anderson KM, Levy D. Influence of contemporary versus 30-year blood pressure levels on left ventricular mass and geometry: the Framingham Heart Study. J Am Coll Cardiol 1991; 18: 1287-94 - 心筋梗塞存在下における低拡張期血圧と冠動脈疾患死の関係
D'Agostino RB, Belanger AJ, Kannel WB, Cruickshank JM. Relation of low diastolic blood pressure to coronary heart disease death in presence of myocardial infarction: the Framingham Study. BMJ 1991; 303: 385-9 - 脳卒中の独立したリスクとしての心房細動
Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991; 22: 983-8 - 左室重量と左室形態への肥満の影響
Lauer MS, Anderson KM, Kannel WB, Levy D. The impact of obesity on left ventricular mass and geometry. The Framingham Heart Study. JAMA 1991; 266: 231-6 - 明らかな糖尿病性心筋症の存在の心エコー上の証拠
Galderisi M, Anderson KM, Wilson PW, Levy D. Echocardiographic evidence for the existence of a distinct diabetic cardiomyopathy (the Framingham Heart Study). Am J Cardiol 1991; 68: 85-9 - QRS間隔は冠動脈疾患発症を予測できない
Kreger BE, Anderson KM, Levy D. QRS interval fails to predict coronary disease incidence. The Framingham Study. Arch Intern Med 1991; 151: 1365-8 - 男性における冠動脈疾患の予測因子としての食物中脂肪
Posner BM, Cobb JL, Belanger AJ, Cupples LA, D'Agostino RB, Stokes J. Dietary lipid predictors of coronary heart disease in men. The Framingham Study. Arch Intern Med 1991; 151: 1181-7 - 運動誘発性ST下降の心拍数による補正
Okin PM, Anderson KM, Levy D, Kligfield P. Heart rate adjustment of exercise-induced ST segment depression. Improved risk stratification in the Framingham Offspring Study. Circulation 1991; 83: 866-74 - アルコール摂取量と左室重量
Manolio TA, Levy D, Garrison RJ, Castelli WP, Kannel WB. Relation of alcohol intake to left ventricular mass: The Framingham Study. J Am Coll Cardiol 1991; 17: 717-21 - 脳卒中の可能性:FHSのリスクプロフィールから
Wolf PA, D'Agostino RB, Belanger AJ, Kannel WB. Probability of stroke: a risk profile from the Framingham Study. Stroke 1991; 22: 312-8 - 高血糖は心血管疾患と関係するか
Wilson PW, Cupples LA, Kannel WB. Is hyperglycemia associated with cardiovascular disease? The Framingham Study. Am Heart J 1991; 121: 586-90 - 健常人におけるQT間隔と総死亡,心血管死亡
Goldberg RJ, Bengtson J, Chen ZY, Anderson KM, Locati E, Levy D. Duration of the QT interval and total and cardiovascular mortality in healthy persons (The Framingham Heart Study experience). Am J Cardiol 1991; 67: 55-8 - 高血圧治療下の中年の12年間冠動脈疾患の発症
Wilson PW, Anderson KM, Castelli WP. Twelve-year incidence of coronary heart disease in middle-aged adults during the era of hypertensive therapy: the Framingham offspring study. Am J Med 1991; 90: 11-6 - 正常高値血圧から高血圧への進展
Leitschuh M, Cupples LA, Kannel W, Gagnon D, Chobanian A. High-normal blood pressure progression to hypertension in the Framingham Heart Study. Hypertension 1991; 17: 22-7 - 左室肥大の臨床的意義
Levy D. Clinical significance of left ventricular hypertrophy: insights from the Framingham Study. J Cardiovasc Pharmacol 1991; 17 Suppl 2: S1-6 - 局部肥満と心血管疾患
Kannel WB, Cupples LA, Ramaswami R, Stokes J, Kreger BE, Higgins M. Regional obesity and risk of cardiovascular disease; the Framingham Study. J Clin Epidemiol 1991; 44: 183-90 - 女性における喫煙と合併症のない狭心症の間の負の相関
Seltzer CC. The negative association in women between cigarette smoking and uncomplicated angina pectoris in the Framingham Heart Study data. J Clin Epidemiol 1991; 44: 871-6; discussion 877-80
- 肥満関連高血圧は心血管疾患リスクが低いか
Kannel WB, Zhang T, Garrison RJ. Is obesity-related hypertension less of a cardiovascular risk? The Framingham Study. Am Heart J 1990; 120: 1195-201 - 大動脈石灰化プラークと心血管疾患
Witteman JC, Kannel WB, Wolf PA, Grobbee DE, Hofman A, D'Agostino RB, Cobb JC. Aortic calcified plaques and cardiovascular disease (the Framingham Study). Am J Cardiol 1990; 66: 1060-4 - 親の病歴は冠動脈疾患の独立した危険因子である
Myers RH, Kiely DK, Cupples LA, Kannel WB. Parental history is an independent risk factor for coronary artery disease: the Framingham Study. Am Heart J 1990; 120: 963-9 - 閉経後女性におけるホルモン補充療法の有無によるアポリポ蛋白とLDL副分画の差異
Campos H, Wilson PW, Jiménez D, McNamara JR, Ordovas J, Schaefer EJ. Differences in apolipoproteins and low-density lipoprotein subfractions in postmenopausal women on and off estrogen therapy: results from the Framingham Offspring Study. Metabolism 1990; 39: 1033-8 - 胸部不快感を有する患者の冠動脈疾患のリスク
Murabito JM, Anderson KM, Kannel WB, Evans JC, Levy D. Risk of coronary heart disease in subjects with chest discomfort: the Framingham Heart Study. Am J Med 1990; 89: 297-302 - 危険因子の変化と心血管疾患による死亡の減少
Sytkowski PA, Kannel WB, D'Agostino RB. Changes in risk factors and the decline in mortality from cardiovascular disease. The Framingham Heart Study. N Engl J Med 1990; 322: 1635-41 - 心エコー図で求めた左室重量による予後判定
Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990; 322: 1561-6 - 糖尿病例で認められた末梢動脈に関する疫学
Abbott RD, Brand FN, Kannel WB. Epidemiology of some peripheral arterial findings in diabetic men and women: experiences from the Framingham Study. Am J Med 1990; 88: 376-81 - 冠動脈疾患のリスクによる患者層別化
Levy D, Wilson PW, Anderson KM, Castelli WP. Stratifying the patient at risk from coronary disease: new insights from the Framingham Heart Study. Am Heart J 1990; 119: 712-7; discussion 717 - Q波梗塞後の心エコーの予後的意義
Wong ND, Levy D, Kannel WB. Prognostic significance of the electrocardiogram after Q wave myocardial infarction. The Framingham Study. Circulation 1990; 81: 780-9 - 身体の大きさ,血圧,身体活動と心エコー図上の左室重量との関係
Savage DD, Levy D, Dannenberg AL, Garrison RJ, Castelli WP. Association of echocardiographic left ventricular mass with body size, blood pressure and physical activity (the Framingham Study). Am J Cardiol 1990; 65: 371-6 - 低収縮期血圧に対するまれな遺伝子のエビデンス
Carter CL, Kannel WB. Evidence of a rare gene for low systolic blood pressure in the Framingham Heart Study. Hum Hered 1990; 40: 235-41 - 縦断的血圧測定と降圧薬服用,認知機能
Farmer ME, Kittner SJ, Abbott RD, Wolz MM, Wolf PA, White LR. Longitudinally measured blood pressure, antihypertensive medication use, and cognitive performance: the Framingham Study. J Clin Epidemiol 1990; 43: 475-80
- 45歳から64歳女性のアルコール摂取の心理社会的関係
Hamlett K, Eaker ED, Stokes J. Psychosocial correlates of alcohol intake among women aged 45 to 64 years: the Framingham Study. J Behav Med 1989; 12: 525-42 - 健常人における年齢の心エコー上左室重量への影響
Dannenberg AL, Levy D, Garrison RJ. Impact of age on echocardiographic left ventricular mass in a healthy population (the Framingham Study). Am J Cardiol 1989; 64: 1066-8 - 高齢者における臨床的に明らかなヘルペスウイルス感染と冠動脈疾患発症のありえそうにない関係
Havlik RJ, Blackwelder WC, Kaslow R, Castelli W. Unlikely association between clinically apparent herpesvirus infection and coronary incidence at older ages. The Framingham Heart Study. Arteriosclerosis 1989; 9: 877-80 - 親の心疾患発症年齢および性と冠動脈リスクの関係
Schildkraut JM, Myers RH, Cupples LA, Kiely DK, Kannel WB. Coronary risk associated with age and sex of parental heart disease in the Framingham Study. Am J Cardiol 1989; 64: 555-9 - 初発心筋梗塞後の長期冠動脈予後に対する危険因子
Wong ND, Cupples LA, Ostfeld AM, Levy D, Kannel WB. Risk factors for long-term coronary prognosis after initial myocardial infarction: the Framingham Study. Am J Epidemiol 1989; 130: 469-80 - 高齢者における呼吸機能,呼吸器症状と関係する死亡
Sorlie PD, Kannel WB, O'Connor G. Mortality associated with respiratory function and symptoms in advanced age. The Framingham Study. Am Rev Respir Dis 1989; 140: 379-84 - コレステロール危険因子スクリーニングに対するガイドラインの影響
Wilson PW, Christiansen JC, Anderson KM, Kannel WB. Impact of national guidelines for cholesterol risk factor screening. The Framingham Offspring Study. JAMA 1989; 262: 41-4 - 初発脳卒中後の無症候性脳卒中の有病率
Kase CS, Wolf PA, Chodosh EH, Zacker HB, Kelly-Hayes M, Kannel WB, D'Agostino RB, Scampini L. Prevalence of silent stroke in patients presenting with initial stroke: the Framingham Study. Stroke 1989; 20: 850-2 - タイプA行動のタイプB行動と比較した合併症のない狭心症の頻度
Eaker ED, Abbott RD, Kannel WB. Frequency of uncomplicated angina pectoris in type A compared with type B persons (the Framingham Study). Am J Cardiol 1989; 63: 1042-5 - コーヒー摂取は心血管疾患に寄与するか
Wilson PW, Garrison RJ, Kannel WB, McGee DL, Castelli WP. Is coffee consumption a contributor to cardiovascular disease? Insights from the Framingham Study. Arch Intern Med 1989; 149: 1169-72 - 心血管疾患の危険因子としての血圧
Stokes J, Kannel WB, Wolf PA, D'Agostino RB, Cupples LA. Blood pressure as a risk factor for cardiovascular disease. The Framingham Study--30 years of follow-up. Hypertension 1989; 13: I13-8 - 一般住民における心室内ブロックの頻度
Kreger BE, Anderson KM, Kannel WB. Prevalence of intraventricular block in the general population: the Framingham Study. Am Heart J 1989; 117: 903-10 - 糖尿病,間欠性跛行と心血管イベントのリスク
Brand FN, Abbott RD, Kannel WB. Diabetes, intermittent claudication, and risk of cardiovascular events. The Framingham Study. Diabetes 1989; 38: 504-9 - 健康な80代の血清リポ蛋白:HDLコレステロール値の減少
Schaefer EJ, Moussa PB, Wilson PW, McGee D, Dallal G, Castelli WP. Plasma lipoproteins in healthy octogenarians: lack of reduced high density lipoprotein cholesterol levels: results from the Framingham Heart Study. Metabolism 1989; 38: 293-6 - 心血管疾患に対するエストロゲンの効果
Wilson PW. The impact of estrogen on cardiovascular disease. Prospective studies: The Framingham Study. Postgrad Med 1989; Spec No: 51-3; discussion 89-90 - 健常人における心血管危険因子と段階的トレッドミル試験耐容能
Abbott RD, Levy D, Kannel WB, Castelli WP, Wilson PW, Garrison RJ, Stokes J. Cardiovascular risk factors and graded treadmill exercise endurance in healthy adults: The Framingham Offspring Study. Am J Cardiol 1989; 63: 342-6 - 高齢者コホートにおける左室重量と冠動脈疾患発症
Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Left ventricular mass and incidence of coronary heart disease in an elderly cohort. The Framingham Heart Study. Ann Intern Med 1989; 110: 101-7 - 余暇時間の身体活動:種類,季節変化,危険因子の相関
Dannenberg AL, Keller JB, Wilson PW, Castelli WP. Leisure time physical activity in the Framingham Offspring Study. Description, seasonal variation, and risk factor correlates. Am J Epidemiol 1989; 129: 76-88 - 55歳から64歳の冠動脈疾患の傾向と危険因子
D'Agostino RB, Kannel WB, Belanger AJ, Sytkowski PA. Trends in CHD and risk factors at age 55-64 in the Framingham Study. Int J Epidemiol 1989; 18: S67-72
- 女性と比較した男性における心筋梗塞後の生存におよぼす糖尿病の影響
Abbott RD, Donahue RP, Kannel WB, Wilson PW. The impact of diabetes on survival following myocardial infarction in men vs women. The Framingham Study. JAMA 1988; 260: 3456-60 - タイプA行動と冠動脈疾患による死亡
Eaker ED, Castelli WP. Type A behavior and mortality from coronary disease in the Framingham study. N Engl J Med 1988; 319: 1480-1 - HDLコレステロールと死亡率
Wilson PW, Abbott RD, Castelli WP. High density lipoprotein cholesterol and mortality. The Framingham Heart Study. Arteriosclerosis 1988; 8: 737-41 - 65歳以上での冠動脈疾患危険因子の比例ハザード解析
Harris T, Cook EF, Kannel WB, Goldman L. Proportional hazards analysis of risk factors for coronary heart disease in individuals aged 65 or older. The Framingham Heart Study. J Am Geriatr Soc 1988; 36: 1023-8 - 高齢者における高血圧のリスクと疫学
Vokonas PS, Kannel WB, Cupples LA. Epidemiology and risk of hypertension in the elderly: the Framingham Study. J Hypertens Suppl 1988; 6: S3-9 - 2型糖尿病における糖尿病性網膜症と心血管疾患
Hiller R, Sperduto RD, Podgor MJ, Ferris FL, Wilson PW. Diabetic retinopathy and cardiovascular disease in type II diabetics. The Framingham Heart Study and the Framingham Eye Study. Am J Epidemiol 1988; 128: 402-9 - 冠動脈疾患のリスクとしてのコレステロールと脂質
Castelli WP. Cholesterol and lipids in the risk of coronary artery disease--the Framingham Heart Study. Can J Cardiol 1988; 4 Suppl A: 5A-10A - 高血圧の発症率
Dannenberg AL, Garrison RJ, Kannel WB. Incidence of hypertension in the Framingham Study. Am J Public Health 1988; 78: 676-9 - 脳卒中後の生存と施設入所に影響する因子
Kelly-Hayes M, Wolf PA, Kannel WB, Sytkowski P, D'Agostino RB, Gresham GE. Factors influencing survival and need for institutionalization following stroke: the Framingham Study. Arch Phys Med Rehabil 1988; 69: 415-8 - HDLコレステロール,総コレステロールスクリーニングと心筋梗塞
Abbott RD, Wilson PW, Kannel WB, Castelli WP. High density lipoprotein cholesterol, total cholesterol screening, and myocardial infarction. The Framingham Study. Arteriosclerosis 1988; 8: 207-11 - 心不全と突然死
Kannel WB, Plehn JF, Cupples LA. Cardiac failure and sudden death in the Framingham Study. Am Heart J 1988; 115: 869-75 - 非喫煙高齢者におけるBMIと死亡率
Harris T, Cook EF, Garrison R, Higgins M, Kannel W, Goldman L. Body mass index and mortality among nonsmoking older persons. The Framingham Heart Study. JAMA 1988; 259: 1520-4 - 静脈瘤の疫学
Brand FN, Dannenberg AL, Abbott RD, Kannel WB. The epidemiology of varicose veins: the Framingham Study. Am J Prev Med 1988; 4: 96-101 - 高血圧,降圧薬治療,冠動脈突然死
Kannel WB, Cupples LA, D'Agostino RB, Stokes J. Hypertension, antihypertensive treatment, and sudden coronary death. The Framingham Study. Hypertension 1988; 11: II45-50 - 脳卒中の危険因子としての喫煙
Wolf PA, D'Agostino RB, Kannel WB, Bonita R, Belanger AJ. Cigarette smoking as a risk factor for stroke. The Framingham Study. JAMA 1988; 259: 1025-9 - 心エコー上で検知された左室肥大:危険因子の頻度
Levy D, Anderson KM, Savage DD, Kannel WB, Christiansen JC, Castelli WP. Echocardiographically detected left ventricular hypertrophy: prevalence and risk factors. The Framingham Heart Study. Ann Intern Med 1988; 108: 7-13 - 痛風と冠動脈疾患
Abbott RD, Brand FN, Kannel WB, Castelli WP. Gout and coronary heart disease: the Framingham Study. J Clin Epidemiol 1988; 41: 237-42
- 血圧と認知機能
Farmer ME, White LR, Abbott RD, Kittner SJ, Kaplan E, Wolz MM, Brody JA, Wolf PA. Blood pressure and cognitive performance. The Framingham Study. Am J Epidemiol 1987; 126: 1103-14 - 一般住民におけるリポ蛋白コレステロールの縦断的,長期的傾向
Anderson KM, Wilson PW, Garrison RJ, Castelli WP. Longitudinal and secular trends in lipoprotein cholesterol measurements in a general population sample. The Framingham Offspring Study. Atherosclerosis 1987; 68: 59-66 - 心臓突然死発症の日内変動
Willich SN, Levy D, Rocco MB, Tofler GH, Stone PH, Muller JE. Circadian variation in the incidence of sudden cardiac death in the Framingham Heart Study population. Am J Cardiol 1987; 60: 801-6 - 複合スコアリング:手法と予測の妥当性
Kannel WB, McGee DL. Composite scoring--methods and predictive validity: insights from the Framingham Study. Health Serv Res 1987; 22: 499-535 - フィブリノーゲンと心血管疾患のリスク
Kannel WB, Wolf PA, Castelli WP, D'Agostino RB. Fibrinogen and risk of cardiovascular disease. The Framingham Study. JAMA 1987; 258: 1183-6 - 左室肥大の心室性不整脈に対するリスク
Levy D, Anderson KM, Savage DD, Balkus SA, Kannel WB, Castelli WP. Risk of ventricular arrhythmias in left ventricular hypertrophy: the Framingham Heart Study. Am J Cardiol 1987; 60: 560-5 - 心房細動:高齢者の脳卒中への主要な原因
Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation: a major contributor to stroke in the elderly. The Framingham Study. Arch Intern Med 1987; 147: 1561-4 - LDL副分画への性差,年齢,脂質状態の影響
McNamara JR, Campos H, Ordovas JM, Peterson J, Wilson PW, Schaefer EJ. Effect of gender, age, and lipid status on low density lipoprotein subfraction distribution. Results from the Framingham Offspring Study. Arteriosclerosis 1987; 7: 483-90 - 女性の冠動脈疾患に対する代謝危険因子
Kannel WB. Metabolic risk factors for coronary heart disease in women: perspective from the Framingham Study. Am Heart J 1987; 114: 413-9 - 心拍数と心血管死亡
Kannel WB, Kannel C, Paffenbarger RS, Cupples LA. Heart rate and cardiovascular mortality: the Framingham Study. Am Heart J 1987; 113: 1489-94 - 35歳から64歳の心血管疾患のさまざまな徴候に対する危険因子の相対的重要度
Stokes J, Kannel WB, Wolf PA, Cupples LA, D'Agostino RB. The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study. Circulation 1987; 75: V65-73 - 成人における冠リスクの予測
Wilson PW, Castelli WP, Kannel WB. Coronary risk prediction in adults (the Framingham Heart Study) Am J Cardiol 1987; 59: 91G-94G - コレステロールと死亡率:30年の追跡から
Anderson KM, Castelli WP, Levy D. Cholesterol and mortality. 30 years of follow-up from the Framingham study. JAMA 1987; 257: 2176-80 - 左室肥大の心エコー基準
Levy D, Savage DD, Garrison RJ, Anderson KM, Kannel WB, Castelli WP. Echocardiographic criteria for left ventricular hypertrophy: the Framingham Heart Study. Am J Cardiol 1987; 59: 956-60 - フィブリノーゲン,喫煙と心血管疾患リスク
Kannel WB, D'Agostino RB, Belanger AJ. Fibrinogen, cigarette smoking, and risk of cardiovascular disease: insights from the Framingham Study. Am Heart J 1987; 113: 1006-10 - 高血圧の寛解:血圧治療の「自然」歴
Dannenberg AL, Kannel WB. Remission of hypertension. The 'natural' history of blood pressure treatment in the Framingham Study. JAMA 1987; 257: 1477-83 - 明らかな心疾患における突然死リスク
Kannel WB, Cupples LA, D'Agostino RB. Sudden death risk in overt coronary heart disease: the Framingham Study. Am Heart J 1987; 113: 799-804 - 予測できない突然死の心エコー上の前駆症状
Kreger BE, Kannel WB, Cupples LA. Electrocardiographic precursors of sudden unexpected death: the Framingham Study. Circulation 1987; 75: II22-4 - 若年成人の高血圧の発症率と前駆症状
Garrison RJ, Kannel WB, Stokes J, Castelli WP. Incidence and precursors of hypertension in young adults: the Framingham Offspring Study. Prev Med 1987; 16: 235-51 - 突然死の心電図上の予測因子
Kreger BE, Cupples LA, Kannel WB. The electrocardiogram in prediction of sudden death: Framingham Study experience. Am Heart J 1987; 113: 377-82 - 冠動脈疾患の予測因子としての非特異的心電図異常
Kannel WB, Anderson K, McGee DL, Degatano LS, Stampfer MJ. Nonspecific electrocardiographic abnormality as a predictor of coronary heart disease: the Framingham Study. Am Heart J 1987; 113: 370-6 - 疫学に心エコーズを用いることに関する考察
Savage DD, Garrison RJ, Kannel WB, Anderson SJ, Feinleib M, Castelli WP. Considerations in the use of echocardiography in epidemiology. The Framingham Study. Hypertension 1987; 9: II40-4 - 一般住民における左室肥大の多様性
Savage DD, Garrison RJ, Kannel WB, Levy D, Anderson SJ, Stokes J, Feinleib M, Castelli WP. The spectrum of left ventricular hypertrophy in a general population sample: the Framingham Study. Circulation 1987; 75: I26-33 - 左室肥大と心不全のリスク
Kannel WB, Levy D, Cupples LA. Left ventricular hypertrophy and risk of cardiac failure: insights from the Framingham Study. J Cardiovasc Pharmacol 1987; 10 Suppl 6: S135-40 - 登録時と追跡14年時での肺機能への喫煙の影響
Sorlie P, Lakatos E, Kannel WB, Celli B. Influence of cigarette smoking on lung function at baseline and at follow-up in 14 years: the Framingham Study. J Chronic Dis 1987; 40: 849-56 - 良好な機能の予測因子
Pinsky JL, Leaverton PE, Stokes J. Predictors of good function: the Framingham Study. J Chronic Dis 1987; 40 Suppl 1: 159S-167S, 181S-2
- 冠動脈疾患の発症とリポ蛋白コレステロール値
Castelli WP, Garrison RJ, Wilson PW, Abbott RD, Kalousdian S, Kannel WB. Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study. JAMA 1986; 256: 2835-8 - 冠動脈疾患の心理社会的およびそのほかの特性
Kannel WB, Eaker ED. Psychosocial and other features of coronary heart disease: insights from the Framingham Study. Am Heart J 1986; 112: 1066-73 - 無症候性心筋虚血と心筋梗塞
Kannel WB. Silent myocardial ischemia and infarction: insights from the Framingham Study. Cardiol Clin 1986; 4: 583-91 - 身体活動と職務上の身体的負荷と心血管疾患および死亡のリスク
Kannel WB, Belanger A, D'Agostino R, Israel I. Physical activity and physical demand on the job and risk of cardiovascular disease and death: the Framingham Study. Am Heart J 1986; 112: 820-5 - 高齢者における糖尿病の疫学
Wilson PW, Anderson KM, Kannel WB. Epidemiology of diabetes mellitus in the elderly. The Framingham Study. Am J Med 1986; 80: 3-9 - リスクのある集団:高血圧のなかの高コレステロール値の頻度
Castelli WP, Anderson K. A population at risk. Prevalence of high cholesterol levels in hypertensive patients in the Framingham Study. Am J Med 1986; 80: 23-32 - 無症候性左室肥大と未認識の心筋梗塞の予後の比較
Kannel WB, Abbott RD. A prognostic comparison of asymptomatic left ventricular hypertrophy and unrecognized myocardial infarction: the Framingham Study. Am Heart J 1986; 111: 391-7 - 全身性高血圧と加齢性黄斑変性症
Sperduto RD, Hiller R. Systemic hypertension and age-related maculopathy in the Framingham Study. Arch Ophthalmol 1986; 104: 216-9
- 孤立性心房細動の特性と予後
Brand FN, Abbott RD, Kannel WB, Wolf PA. Characteristics and prognosis of lone atrial fibrillation. 30-year follow-up in the Framingham Study. JAMA 1985; 254: 3449-53 - 体重と30年間死亡率
Garrison RJ, Castelli WP. Weight and thirty-year mortality of men in the Framingham Study. Ann Intern Med 1985; 103: 1006-9 - 脂質,糖尿病,冠動脈疾患
Kannel WB. Lipids, diabetes, and coronary heart disease: insights from the Framingham Study. Am Heart J 1985; 110: 1100-7 - 50歳以上の女性における閉経後のエストロゲン服用,喫煙と心血管疾患罹病率
Wilson PW, Garrison RJ, Castelli WP. Postmenopausal estrogen use, cigarette smoking, and cardiovascular morbidity in women over 50. The Framingham Study. N Engl J Med 1985; 313: 1038-43 - リウマチ性心疾患の予後
Goetzler R, Stokes J, Anderson K. Prognosis of subjects in the Framingham Study with rheumatic heart disease. J Am Geriatr Soc 1985; 33: 693-7 - 甲状腺の加齢:甲状腺疾患
Sawin CT, Castelli WP, Hershman JM, McNamara P, Bacharach P. The aging thyroid. Thyroid deficiency in the Framingham Study. Arch Intern Med 1985; 145: 1386-8 - 高齢者の聴力低下
Mo?cicki EK, Elkins EF, Baum HM, McNamara PM. Hearing loss in the elderly: an epidemiologic study of the Framingham Heart Study Cohort. Ear Hear 1985; 6: 184-90 - 孤立性失神の疫学的特徴
Savage DD, Corwin L, McGee DL, Kannel WB, Wolf PA. Epidemiologic features of isolated syncope: the Framingham Study. Stroke 1985; 16: 626-9 - 新規左脚ブロック発症の臨床,心電図関連因子
Schneider JF, Thomas HE, McNamara PM, Kannel WB. Clinical-electrocardiographic correlates of newly acquired left bundle branch block: the Framingham Study. Am J Cardiol 1985; 55: 1332-8 - 高血圧と診断されていない心筋梗塞
Kannel WB, Dannenberg AL, Abbott RD. Unrecognized myocardial infarction and hypertension: the Framingham Study. Am Heart J 1985; 109: 581-5 - 冠動脈疾患の危険因子としての高尿酸血症
Brand FN, McGee DL, Kannel WB, Stokes J, Castelli WP. Hyperuricemia as a risk factor of coronary heart disease: The Framingham Study. Am J Epidemiol 1985; 121: 11-8 - 突然死の疫学
Kannel WB, McGee DL. Epidemiology of sudden death: insights from the Framingham Study. Cardiovasc Clin 1985; 15: 93-105 - 高血圧の治療とその心血管危険因子におよぼす影響
Shea S, Cook EF, Kannel WB, Goldman L. Treatment of hypertension and its effect on cardiovascular risk factors: data from the Framingham Heart Study. Circulation 1985; 71: 22-30 - 間欠性跛行のいくつかの疫学的特徴のアップデート
Kannel WB, McGee DL. Update on some epidemiologic features of intermittent claudication: the Framingham Study. J Am Geriatr Soc 1985; 33: 13-8 - 脂質,耐糖能異常と血管疾患
Wilson PW, Kannel WB, Anderson KM. Lipids, glucose intolerance and vascular disease: the Framingham Study. Monogr Atheroscler 1985; 13: 1-11
- 突然死:性,冠動脈疾患の状態による発症率と危険因子の差異
Schatzkin A, Cupples LA, Heeren T, Morelock S, Kannel WB. Sudden death in the Framingham Heart Study. Differences in incidence and risk factors by sex and coronary disease status. Am J Epidemiol 1984; 120: 888-99 - 蛋白尿の予後
Kannel WB, Stampfer MJ, Castelli WP, Verter J. The prognostic significance of proteinuria: the Framingham study. Am Heart J 1984; 108: 1347-52 - 診断されていない心筋梗塞の発症率と予後
Kannel WB, Abbott RD. Incidence and prognosis of unrecognized myocardial infarction. An update on the Framingham study. N Engl J Med 1984; 311: 1144-7 - 飲酒と死亡率
Gordon T, Kannel WB. Drinking and mortality. The Framingham Study. Am J Epidemiol 1984; 120: 97-107 - くも膜下,脳内出血:自然歴,予後と前駆因子
Sacco RL, Wolf PA, Bharucha NE, Meeks SL, Kannel WB, Charette LJ, McNamara PM, Palmer EP, D'Agostino R. Subarachnoid and intracerebral hemorrhage: natural history, prognosis, and precursive factors in the Framingham Study. Neurology 1984; 34: 847-54 - 予測されていない突然死の疫学:男性と女性の危険因子
Schatzkin A, Cupples LA, Heeren T, Morelock S, Mucatel M, Kannel WB. The epidemiology of sudden unexpected death: risk factors for men and women in the Framingham Heart Study. Am Heart J 1984; 107: 1300-6 - 冠動脈疾患の疫学
Castelli WP. Epidemiology of coronary heart disease: the Framingham study. Am J Med 1984; 76: 4-12 - 身長と相対的体重の家族的類似
Heller R, Garrison RJ, Havlik RJ, Feinleib M, Padgett S. Family resemblances in height and relative weight in the Framingham Heart Study. Int J Obes 1984; 8: 399-405 - 非侵襲的心臓病学ツールと遺伝疫学の評価項目
Savage D, Padgett S, Myers R, Anderson S, Levy D, Plehn J, Finizola B, Castelli W. Noninvasive cardiology tools and endpoints in genetic epidemiology: the Framingham Study. Prog Clin Biol Res 1984; 147: 407-17
- 脳卒中の素因となる冠動脈疾患の症状
Kannel WB, Wolf PA, Verter J. Manifestations of coronary disease predisposing to stroke. The Framingham study. JAMA 1983; 250: 2942-6 - 一般住民における僧帽弁逸脱症:不整脈
Savage DD, Levy D, Garrison RJ, Castelli WP, Kligfield P, Devereux RB, Anderson SJ, Kannel WB, Feinleib M. Mitral valve prolapse in the general population. 3. Dysrhythmias: the Framingham Study. Am Heart J 1983; 106: 582-6 - 一般住民における僧帽弁逸脱症:臨床的特徴
Savage DD, Devereux RB, Garrison RJ, Castelli WP, Anderson SJ, Levy D, Thomas HE, Kannel WB, Feinleib M. Mitral valve prolapse in the general population. 2. Clinical features: the Framingham Study. Am Heart J 1983; 106: 577-81 - 一般住民における僧帽弁逸脱症:疫学的特性
Savage DD, Garrison RJ, Devereux RB, Castelli WP, Anderson SJ, Levy D, McNamara PM, Stokes J, Kannel WB, Feinleib M. Mitral valve prolapse in the general population. 1. Epidemiologic features: the Framingham Study. Am Heart J 1983; 106: 571-6 - 心房細動の持続期間と脳卒中の切迫度
Wolf PA, Kannel WB, McGee DL, Meeks SL, Bharucha NE, McNamara PM. Duration of atrial fibrillation and imminence of stroke: the Framingham study. Stroke 1983; 14: 664-7 - 冠動脈疾患と心房細動
Kannel WB, Abbott RD, Savage DD, McNamara PM. Coronary heart disease and atrial fibrillation: the Framingham Study. Am Heart J 1983; 106: 389-96 - 男性にとっての伴侶の行動と冠動脈疾患:タイプA行動の夫のリスクに対する配偶者の社会的,心理学的状態による修飾
Eaker ED, Haynes SG, Feinleib M. Spouse behavior and coronary heart disease in men: prospective results from the Framingham heart study. II. Modification of risk in type A husbands according to the social and psychological status of their wives. Am J Epidemiol 1983; 118: 23-41 - 男性にとっての伴侶の行動と冠動脈疾患:危険因子の索引と心理社会的状態の冠疾患との関係
Haynes SG, Eaker ED, Feinleib M. Spouse behavior and coronary heart disease in men: prospective results from the Framingham heart study. I. Concordance of risk factors and the relationship of psychosocial status to coronary incidence. Am J Epidemiol 1983; 118: 1-22 - 飲酒とその喫煙,血圧値,血清脂質値,尿酸値との関係
Gordon T, Kannel WB. Drinking and its relation to smoking, BP, blood lipids, and uric acid. The Framingham study. Arch Intern Med 1983; 143: 1366-74 - 肺塞栓症の危険因子
Goldhaber SZ, Savage DD, Garrison RJ, Castelli WP, Kannel WB, McNamara PM, Gherardi G, Feinleib M. Risk factors for pulmonary embolism. The Framingham Study. Am J Med 1983; 74: 1023-8 - 一般住民におけるsubmitralカルシウムの有病率とその関連因子
Savage DD, Garrison RJ, Castelli WP, McNamara PM, Anderson SJ, Kannel WB, Feinleib M. Prevalence of submitral (anular) calcium and its correlates in a general population-based sample (the Framingham Study). Am J Cardiol 1983; 51: 1375-8 - リポ蛋白値に関連する因子
Wilson PW, Garrison RJ, Abbott RD, Castelli WP. Factors associated with lipoprotein cholesterol levels. The Framingham study. Arteriosclerosis 1983; 3: 273-81 - リポ蛋白コレステロールのクラスの結合分布
Abbott RD, Garrison RJ, Wilson PW, Epstein FH, Castelli WP, Feinleib M, LaRue C. Joint distribution of lipoprotein cholesterol classes. The Framingham study. Arteriosclerosis 1983; 3: 260-72 - 心血管疾患の独立危険因子としての肥満:26年間の追跡から
Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 1983; 67: 968-77 - 相対体重と長期的な死亡との関係への交絡因子としての喫煙
Garrison RJ, Feinleib M, Castelli WP, McNamara PM. Cigarette smoking as a confounder of the relationship between relative weight and long-term mortality. The Framingham Heart Study. JAMA 1983; 249: 2199-203 - 飲酒習慣と心血管疾患
Gordon T, Kannel WB. Drinking habits and cardiovascular disease: the Framingham Study. Am Heart J 1983; 105: 667-73 - 自由生活者におけるposterior extra echocardiographic spacesの有病率と関連因子
Savage DD, Garrison RJ, Brand F, Anderson SJ, Castelli WP, Kannel WB, Feinleib M. Prevalence and correlates of posterior extra echocardiographic spaces in a free-living population based sample (the Framingham study). Am J Cardiol 1983; 51: 1207-12 - 心血管疾患の予測因子としての肺活量
Kannel WB, Hubert H, Lew EA. Vital capacity as a predictor of cardiovascular disease: the Framingham study. Am Heart J 1983; 105: 311-5 - 24時間心電図モニタリング中の予期していない突然死
Savage DD, Castelli WP, Anderson SJ, Kannel WB. Sudden unexpected death during ambulatory electrocardiographic monitoring. The Framingham Study. Am J Med 1983; 74: 148-52
- 脳卒中の死亡診断の精度
Corwin LE, Wolf PA, Kannel WB, McNamara PM. Accuracy of death certification of stroke: the Framingham Study. Stroke 1982; 13: 818-21 - 脳卒中後の生存率と再発
Sacco RL, Wolf PA, Kannel WB, McNamara PM. Survival and recurrence following stroke. The Framingham study. Stroke 1982; 13: 290-5 - 慢性心房細動の疫学的特性
Kannel WB, Abbott RD, Savage DD, McNamara PM. Epidemiologic features of chronic atrial fibrillation: the Framingham study. N Engl J Med 1982; 306: 1018-22 - 兄弟の冠動脈疾患の予測:多変量評価
Snowden CB, McNamara PM, Garrison RJ, Feinleib M, Kannel WB, Epstein FH. Predicting coronary heart disease in siblings--a multivariate assessment: the Framingham Heart Study. Am J Epidemiol 1982; 115: 217-22 - タイプA行動と冠動脈疾患の10年発症率
Haynes SG, Feinleib M, Eaker ED. Type A behavior and the ten year incidence of coronary heart disease in the Framingham Heart Study. Act Nerv Super (Praha) 1982; Suppl 3: 57-77 - タイプA行動と冠動脈疾患発症
Haynes SG, Feinleib M. Type A behavior and the incidence of coronary heart disease in the Framingham Heart Study. Adv Cardiol 1982; 29: 85-94 - 冠動脈突然死
Kannel WB, Thomas HE. Sudden coronary death: the Framingham Study. Ann N Y Acad Sci 1982; 382: 3-21
- 過去14年間の肥満,VLDL,耐糖能異常
Wilson PW, McGee DL, Kannel WB. Obesity, very low density lipoproteins, and glucose intolerance over fourteen years: The Framingham Study. Am J Epidemiol 1981; 114: 697-704 - リポ蛋白,心血管疾患と死亡
Gordon T, Kannel WB, Castelli WP, Dawber TR. Lipoproteins, cardiovascular disease, and death. The Framingham study. Arch Intern Med 1981; 141: 1128-31 - フィルター付きタバコと冠動脈疾患
Castelli WP, Garrison RJ, Dawber TR, McNamara PM, Feinleib M, Kannel WB. The filter cigarette and coronary heart disease: the Framingham study. Lancet 1981; 2: 109-13 - 無症候性頸動脈雑音と脳卒中のリスク
Wolf PA, Kannel WB, Sorlie P, McNamara P. Asymptomatic carotid bruit and risk of stroke. The Framingham study. JAMA 1981; 245: 1442-5 - 一般住民における新規発症左脚ブロックの比較特性
Schneider JF, Thomas HE, Sorlie P, Kreger BE, McNamara PM, Kannel WB. Comparative features of newly acquired left and right bundle branch block in the general population: the Framingham study. Am J Cardiol 1981; 47: 931-40 - 収縮期血圧,動脈の剛性と脳卒中リスク
Kannel WB, Wolf PA, McGee DL, Dawber TR, McNamara P, Castelli WP. Systolic blood pressure, arterial rigidity, and risk of stroke. The Framingham study. JAMA 1981; 245: 1225-9 - 脂質とリポ蛋白分画のアテローム発生に果たす役割
Kannel WB, Gordon T, Castelli WP. Role of lipids and lipoprotein fractions in atherogenesis: the Framingham study. Prog Lipid Res 1981; 20: 339-48
- 冠動脈疾患の有病率:リポ蛋白コレステロールの役割
Wilson PW, Garrison RJ, Castelli WP, Feinleib M, McNamara PM, Kannel WB. Prevalence of coronary heart disease in the Framingham Offspring Study: role of lipoprotein cholesterols. Am J Cardiol 1980; 46: 649-54 - 肥満とリポ蛋白コレステロール
Garrison RJ, Wilson PW, Castelli WP, Feinleib M, Kannel WB, McNamara PM. Obesity and lipoprotein cholesterol in the Framingham offspring study. Metabolism 1980; 29: 1053-60 - 不安定高血圧:誤った概念か?
Kannel WB, Sorlie P, Gordon T. Labile hypertension: a faulty concept? The Framingham study. Circulation 1980; 61: 1183-7 - 収縮期高血圧の展望
Kannel WB, Dawber TR, McGee DL. Perspectives on systolic hypertension. The Framingham study. Circulation 1980; 61: 1179-82 - ボディービルと死亡率
Sorlie P, Gordon T, Kannel WB. Body build and mortality. The Framingham study. JAMA 1980; 243: 1828-31 - 血圧と心筋梗塞後の生存率
Kannel WB, Sorlie P, Castelli WP, McGee D. Blood pressure and survival after myocardial infarction: the Framingham study. Am J Cardiol 1980; 45: 326-30 - 女性,仕事と冠動脈疾患
Haynes SG, Feinleib M. Women, work and coronary heart disease: prospective findings from the Framingham heart study. Am J Public Health 1980; 70: 133-41 - 冠動脈疾患と心理社会学的関係:8年間の冠動脈疾患発症率
Haynes SG, Feinleib M, Kannel WB. The relationship of psychosocial factors to coronary heart disease in the Framingham Study. III. Eight-year incidence of coronary heart disease. Am J Epidemiol 1980; 111: 37-58 - 新規発症左脚ブロック
Schneider JF, Thomas HE, Kreger BE, McNamara PM, Sorlie P, Kannel WB. Newly acquired right bundle-branch block: The Framingham Study. Ann Intern Med 1980; 92: 37-44
- 脳卒中障害の長期疫学的プロフィール
Gresham GE, Phillips TF, Wolf PA, McNamara PM, Kannel WB, Dawber TR. Epidemiologic profile of long-term stroke disability: the Framingham study. Arch Phys Med Rehabil 1979; 60: 487-91 - 剖検での心血管系の所見と生前の特徴との関係
Feinleib M, Kannel WB, Tedeschi CG, Landau TK, Garrison RJ. The relation of antemortem characteristics to cardiovascular findings at necropsy--The Framingham Study. Atherosclerosis 1979; 34: 145-57 - 家族の冠動脈疾患の調査
Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP. An investigation of coronary heart disease in families. The Framingham offspring study. Am J Epidemiol 1979; 110: 281-90 - 身体活動の健康へのベネフィット
Kannel WB, Sorlie P. Some health benefits of physical activity. The Framingham Study. Arch Intern Med 1979; 139: 857-61 - 初発心筋梗塞後の予後
Kannel WB, Sorlie P, McNamara PM. Prognosis after initial myocardial infarction: the Framingham study. Am J Cardiol 1979; 44: 53-9 - 肥満,脂質と耐糖能異常
Kannel WB, Gordon T, Castelli WP. Obesity, lipids, and glucose intolerance. The Framingham Study. Am J Clin Nutr 1979; 32: 1238-45 - 糖尿病と心血管疾患
Kannel WB, McGee DL. Diabetes and cardiovascular disease. The Framingham study. JAMA 1979; 241: 2035-8 - 新規発症左脚ブロック
Schneider JF, Thomas HE, Kreger BE, McNamara PM, Kannel WB. Newly acquired left bundle-branch block: the Framingham study. Ann Intern Med 1979; 90: 303-10 - 心血管疾患の危険因子としての糖尿病と耐糖能異常
Kannel WB, McGee DL. Diabetes and glucose tolerance as risk factors for cardiovascular disease: the Framingham study. Diabetes Care 1979; 2: 120-6 - コレステロールによるアテローム性疾患の予測
Kannel WB, Castelli WP, Gordon T. Cholesterol in the prediction of atherosclerotic disease. New perspectives based on the Framingham study. Ann Intern Med 1979; 90: 85-91 - 糖尿病と心血管危険因子
Kannel WB, McGee DL. Diabetes and cardiovascular risk factors: the Framingham study. Circulation 1979; 59: 8-13
- 慢性心房細動の疫学的評価と脳卒中のリスク
Wolf PA, Dawber TR, Thomas HE, Kannel WB. Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: the Framingham study. Neurology 1978; 28: 973-7 - 閉経と冠動脈疾患
Gordon T, Kannel WB, Hjortland MC, McNamara PM. Menopause and coronary heart disease. The Framingham Study. Ann Intern Med 1978; 89: 157-61 - 臨床上の狭心症の回復
Kannel WB, Sorlie PD. Remission of clinical angina pectoris: the Framingham study. Am J Cardiol 1978; 42: 119-23 - 高齢者における心血管リスクの評価
Kannel WB, Gordan T. Evaluation of cardiovascular risk in the elderly: the Framingham study. Bull N Y Acad Med 1978; 54: 573-91 - 心理社会学的因子と冠動脈疾患の関係:冠動脈疾患の有病率
Haynes SG, Feinleib M, Levine S, Scotch N, Kannel WB. The relationship of psychosocial factors to coronary heart disease in the Framingham study. II. Prevalence of coronary heart disease. Am J Epidemiol 1978; 107: 384-402 - 心理社会学的因子と冠動脈疾患の関係:方法と危険因子
Haynes SG, Levine S, Scotch N, Feinleib M, Kannel WB. The relationship of psychosocial factors to coronary heart disease in the Framingham study. I. Methods and risk factors. Am J Epidemiol 1978; 107: 362-83 - 喫煙とHDLコレステロール
Garrison RJ, Kannel WB, Feinleib M, Castelli WP, McNamara PM, Padgett SJ. Cigarette smoking and HDL cholesterol: the Framingham offspring study. Atherosclerosis 1978; 30: 17-25 - 初発心筋梗塞後の予後への喫煙の影響
Sparrow D, Dawber TR. The influence of cigarette smoking on prognosis after a first myocardial infarction. A report from the Framingham study. J Chronic Dis 1978; 31: 425-32
- 前胸部T波ベクトルによる冠動脈疾患の探索
Schneider JF, Thomas HE, Kannel WB. Precordial T wave vectors in the detection of coronary heart disease. The Framingham study. Am Heart J 1977; 94: 568-72 - 女性における糖尿病,血清脂質と冠動脈疾患に対する肥満の役割
Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. Diabetes, blood lipids, and the role of obesity in coronary heart disease risk for women. The Framingham study. Ann Intern Med 1977; 87: 393-7 - 冠動脈疾患の「保護因子」としてのHDLコレステロール
Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med 1977; 62: 707-14
- 血圧評価の問題点
Gordon T, Sorlie P, Kannel WB. Problems in the assessment of blood pressure: the Framingham Study. Int J Epidemiol 1976; 5: 327-34 - ABO血液型と心血管疾患
Garrison RJ, Havlik RJ, Harris RB, Feinleib M, Kannel WB, Padgett SJ. ABO blood group and cardiovacular disease: the Framingham study. Atherosclerosis 1976; 25: 311-8 - 閉経と心血管疾患リスク
Kannel WB, Hjortland MC, McNamara PM, Gordon T. Menopause and risk of cardiovascular disease: the Framingham study. Ann Intern Med 1976; 85: 447-52 - 心血管疾患の一般的なリスクプロフィール
Kannel WB, McGee D, Gordon T. A general cardiovascular risk profile: the Framingham Study. Am J Cardiol 1976; 38: 46-51 - 肥満と心血管疾患
Gordon T, Kannel WB. Obesity and cardiovascular diseases: the Framingham study. Clin Endocrinol Metab 1976; 5: 367-75 - 血圧の成分とアテローム血栓性脳梗塞のリスク
Kannel WB, Dawber TR, Sorlie P, Wolf PA. Components of blood pressure and risk of atherothrombotic brain infarction: the Framingham study. Stroke 1976; 7: 327-31 - 閉経に合併するアテローム生成
Hjortland MC, McNamara PM, Kannel WB. Some atherogenic concomitants of menopause: The Framingham Study. Am J Epidemiol 1976; 103: 304-11
- 脳卒中生存者の残存障害
Gresham GE, Fitzpatrick TE, Wolf PA, McNamara PM, Kannel WB, Dawber TR. Residual disability in survivors of stroke--the Framingham study. N Engl J Med 1975; 293: 954-6 - 禁煙に関連する変化
Gordon T, Kannel WB, Dawber TR, McGee D. Changes associated with quitting cigarette smoking: the Framingham Study. Am Heart J 1975; 90: 322-8 - 心血管疾患におよぼす血圧の役割
Kannel WB. Role of blood pressure in cardiovascular disease: the Framingham Study. Angiology 1975; 26: 1-14
- 男性における喫煙中止後の死亡と心臓発作
Gordon T, Kannel WB, McGee D, Dawber TR. Death and coronary attacks in men after giving up cigarette smoking. A report from the Framingham study. Lancet 1974; 2: 1345-8 - 脳梗塞発症における脂質の役割
Kannel WB, Gordon T, Dawber TR. Role of lipids in the development of brain infarction: the Framingham study. Stroke 1974; 5: 679-85 - コーヒーと心血管疾患
Dawber TR, Kannel WB, Gordon T. Coffee and cardiovascular disease. Observations from the framingham study. N Engl J Med 1974; 291: 871-4 - うっ血性心不全に対する糖尿病の役割
Kannel WB, Hjortland M, Castelli WP. Role of diabetes in congestive heart failure: the Framingham study. Am J Cardiol 1974; 34: 29-34 - 肺活量とうっ血性心不全
Kannel WB, Seidman JM, Fercho W, Castelli WP. Vital capacity and congestive heart failure. The Framingham study. Circulation 1974; 49: 1160-6 - 体重変化とアテローム生成形質変化の関係
Ashley FW, Kannel WB. Relation of weight change to changes in atherogenic traits: the Framingham Study. J Chronic Dis 1974; 27: 103-14
- 未認識の心筋梗塞の臨床上の特性:無症候性および症候性
Margolis JR, Kannel WS, Feinleib M, Dawber TR, McNamara PM. Clinical features of unrecognized myocardial infarction--silent and symptomatic. Eighteen year follow-up: the Framingham study. Am J Cardiol 1973; 32: 1-7 - 間欠性跛行の発症と喫煙
Kannel WB, Shurtleff D. The Framingham Study. Cigarettes and the development of intermittent claudication. Geriatrics 1973; 28: 61-8 - アテローム血栓性脳梗塞に対する心機能障害の役割
Wolf PA, Kannel WB, McNamara PM, Gordon T. The role of impaired cardiac function in atherothrombotic brain infarction: the Framingham study. Am J Public Health 1973; 63: 52-8
- うっ血性心不全発症に対する血圧の役割
Kannel WB, Castelli WP, McNamara PM, McKee PA, Feinleib M. Role of blood pressure in the development of congestive heart failure. The Framingham study. N Engl J Med 1972; 287: 781-7 - 頭部,心臓,脚部で動脈硬化になりやすい傾向
Gordon T, Kannel WB. Predisposition to atherosclerosis in the head, heart, and legs. The Framingham study. JAMA 1972; 221: 661-6 - ヘモグロビンと脳梗塞のリスク
Kannel WB, Gordon T, Wolf PA, McNamara P. Hemoglobin and the risk of cerebral infarction: the Framingham Study. Stroke 1972; 3: 409-20 - 狭心症の自然歴:予後と生存率
Kannel WB, Feinleib M. Natural history of angina pectoris in the Framingham study. Prognosis and survival. Am J Cardiol 1972; 29: 154-63
- うっ血性心不全の自然歴
McKee PA, Castelli WP, McNamara PM, Kannel WB. The natural history of congestive heart failure: the Framingham study. N Engl J Med 1971; 285: 1441-6 - 疾患の発症と変化の連続的な計測
Truett J, Sorlie P. Changes in successive measurements and the development of disease: the Framingham Study. J Chronic Dis 1971; 24: 349-61 - 冠動脈疾患のリスクとしての収縮期vs拡張期血圧
Kannel WB, Gordon T, Schwartz MJ. Systolic versus diastolic blood pressure and risk of coronary heart disease. The Framingham study. Am J Cardiol 1971; 27: 335-46 - 冠動脈疾患による若年死亡
Gordon T, Kannel WB. Premature mortality from coronary heart disease. The Framingham study. JAMA 1971; 215: 1617-25 - 血清コレステロール,リポ蛋白と冠動脈疾患リスク
Kannel WB, Castelli WP, Gordon T, McNamara PM. Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study. Ann Intern Med 1971; 74: 1-12
- 脳卒中に対する血圧の役割の疫学的評価
Kannel WB, Wolf PA, Verter J, McNamara PM. Epidemiologic assessment of the role of blood pressure in stroke. The Framingham study. JAMA 1970; 214: 301-10 - 心電図上の左室肥大と冠動脈疾患リスク
Kannel WB, Gordon T, Castelli WP, Margolis JR. Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease. The Framingham study. Ann Intern Med 1970; 72: 813-22 - 間欠性跛行
Kannel WB, Skinner JJ, Schwartz MJ, Shurtleff D. Intermittent claudication. Incidence in the Framingham Study. Circulation 1970; 41: 875-83 - 不顕性心機能障害,うっ血性心不全と塞栓性脳卒中のリスク
Wolf PA, Kannel WB, McNamara PM. Occult impaired cardiac function, congestive heart failure, and risk of thrombotic stroke: the Framingham Study. Neurology 1970; 20: 373 - 未認識の心筋梗塞:14年間の追跡から
Kannel WB, McNamara PM, Feinleib M, Dawber TR. The unrecognized myocardial infarction. Fourteen-year follow-up experience in the Framingham study. Geriatrics 1970; 25: 75-87
- 血清脂質分画と冠動脈疾患リスク
Kannel WB, Castelli WP, McNamara PM. Serum lipid fractions and risk of coronary heart disease. The Framingham study. Minn Med 1969; 52: 1225-30 - 心電図上の左室肥大:有病率,発症率,死亡率
Kannel WB, Gordon T, Offutt D. Left ventricular hypertrophy by electrocardiogram. Prevalence, incidence, and mortality in the Framingham study. Ann Intern Med 1969; 71: 89-105 - 血圧と冠動脈疾患リスク
Kannel WB, Schwartz MJ, McNamara PM. Blood pressure and risk of coronary heart disease: the Framingham study. Dis Chest 1969; 56: 43-52
- 脂肪過多症の血圧と高血圧発症との関連
Kannel WB, Brand N, Skinner JJ, Dawber TR, McNamara PM. The relation of adiposity to blood pressure and development of hypertension. The Framingham study. Ann Intern Med 1967; 67: 48-59 - 冠動脈疾患発症と体重の関係
Kannel WB, LeBauer EJ, Dawber TR, McNamara PM. Relation of body weight to development of coronary heart disease. The Framingham study. Circulation 1967; 35: 734-44
- 2年ごとの継続的コレステロール値計測と冠動脈疾患発症の関係
Kahn HA, Dawber TR. The development of coronary heart disease in relation to sequential biennial measures of cholesterol in the Framingham study. J Chronic Dis 1966; 19: 611-20 - コレステロール-リン脂質比による冠動脈疾患の予測
Thomas HE, Kannel WB, Dawber TR, McNamara PM. Cholesterol-phospholipid ratio in the prediction of coronary heart disease. The Framingham study. N Engl J Med 1966; 274: 701-5 - 胆嚢疾患の疫学
Friedman GD, Kannel WB, Dawber TR. The epidemiology of gallbladder disease: observations in the Framingham Study. J Chronic Dis 1966; 19: 273-92
- 食習慣と心血管疾患:食事摂取の計測
MANN GV, PEARSON G, GORDON T, DAWBER TR. Diet and cardiovascular disease in the Framingham study. I. Measurement of dietary intake. Am J Clin Nutr 1962; 11: 200-25 - 冠動脈疾患の疫学研究における食習慣アセスメント:計測法の信頼性
DAWBER TR, PEARSON G, ANDERSON P, MANN GV, KANNEL WB, SHURTLEFF D, McNAMARA P. Dietary assessment in the epidemiologic study of coronary heart disease: the Framingham study. II. Reliability of measurement. Am J Clin Nutr 1962; 11: 226-34 - 冠動脈疾患の生理学的観点からの疫学的特徴
PRESTON JM. Epidemiological manifestations of the physiological aspects of coronary heart disease. A condensed analysis of the six-year follow-up in the Framingham Study. J S C Med Assoc 1962; 58: 296-8
- 冠動脈疾患発症に関連するいくつか因子:6年間の追跡から
DAWBER TR, KANNEL WB, REVOTSKIE N, STOKES J, KAGAN A, GORDON T. Some factors associated with the development of coronary heart disease: six years' follow-up experience in the Framingham study. Am J Public Health 1959; 49: 1349-56 - 無症候性冠動脈疾患:未認識の心筋梗塞の頻度と臨床特性
STOKES J, DAWBER TR. The silent coronary: the frequency and clinical characteristics of unrecognized myocardial infarction in the Framingham study. Ann Intern Med 1959; 50: 1359-69